Jan J. Sprengers

Measurement of excitation-inhibition ratio in autism spectrum disorder using critical brain dynamics

Hilgo Bruining, Richard Hardstone, Erika L. Juárez-Martinez et al. · Scientific Reports · 2020 · 226 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

Bumetanide for Core Symptoms of Autism Spectrum Disorder (BAMBI): A Single Center, Double-Blinded, Participant-Randomized, Placebo-Controlled, Phase-2 Superiority Trial

Jan J. Sprengers, Dorinde M. van Andel, Nicolaas P. A. Zuithoff et al. · Journal of the American Academy of Child & Adolescent Psychiatry · 2020 · 95 citations · Full text

Medicine, Pharmacotherapy, Psychiatry +14

Effects of bumetanide on neurodevelopmental impairments in patients with tuberous sclerosis complex: an open-label pilot study

Dorinde M. van Andel, Jan J. Sprengers, Bob Oranje et al. · Molecular Autism · 2020 · 53 citations · Full text

Medicine, Neuroscience, Pharmacology +17

Cntn4, a risk gene for neuropsychiatric disorders, modulates hippocampal synaptic plasticity and behavior

Asami Oguro‐Ando, Rosemary A. Bamford, Wiedjai Sital et al. · Translational Psychiatry · 2021 · 49 citations · Full text

Life Sciences, Genetics, Neuroscience +14

Prediction of Behavioral Improvement Through Resting-State Electroencephalography and Clinical Severity in a Randomized Controlled Trial Testing Bumetanide in Autism Spectrum Disorder

Erika L. Juárez-Martinez, Jan J. Sprengers, Gianina Cristian et al. · Biological Psychiatry Cognitive Neuroscience and Neuroimaging · 2021 · 47 citations · Full text

Life Sciences, Neuroscience, Psychiatry +16