Meghan J. Lyle

DNA-damage-inducible (din) loci are transcriptionally activated in competent Bacillus subtilis.

Paul E. Love, Meghan J. Lyle, Ronald E. Yasbin · Proceedings of the National Academy of Sciences · 1985 · 123 citations · Full text

Bacillus Subtilis, Uv Radiation, Natural Sciences +15

Treatment of Hemophilia A Using Factor VIII Messenger RNA Lipid Nanoparticles

Chun‐Yu Chen, Dominic M. Tran, Alex Cavedon et al. · Molecular Therapy — Nucleic Acids · 2020 · 83 citations · Full text

Nanotherapeutics, Engineering, Immunology +18

CD4+ T cells engineered with FVIII-CAR and murine Foxp3 suppress anti-factor VIII immune responses in hemophilia a mice

Richard Y. Fu, Alex C. Chen, Meghan J. Lyle et al. · Cellular Immunology · 2020 · 32 citations · Full text

Inflammation, Autoimmune Disease, T-regulatory Cell +10

Antigen‐specific in vitro expansion of factor VIII‐specific regulatory T cells induces tolerance in hemophilia A mice

Bryn M. Smith, Meghan J. Lyle, Alex C. Chen et al. · Journal of Thrombosis and Haemostasis · 2019 · 20 citations · Full text

Medicine, T-regulatory Cell, Immune Regulation +12

Strategies to target long-lived plasma cells for treating hemophilia A inhibitors

Chao-Lien Liu, Meghan J. Lyle, Simon Shin et al. · Cellular Immunology · 2016 · 19 citations · Full text

Inflammation, Granulocyte, Medicine +9