A defined glycosaminoglycan-binding substratum for human pluripotent stem cells

Joseph R. Klim, Lingyin Li, Paul J. Wrighton, +2

Nature Methods

Regenerative MedicineDefined Glycosaminoglycan-binding SubstratumInduced Pluripotent Stem CellMedicineGlycobiology +5

Substratum-induced differentiation of human pluripotent stem cells reveals the coactivator YAP is a potent regulator of neuronal specification

Samira Musah, Paul J. Wrighton, Yefim Zaltsman, +8

Proceedings of the National Academy of Sciences

Glycosaminoglycan-Binding Hydrogels Enable Mechanical Control of Human Pluripotent Stem Cell Self-Renewal

Samira Musah, Stephen A. Morin, Paul J. Wrighton, +3

ACS Nano

Tissue EngineeringEngineeringCell AdhesionBiomaterials DesignBiomedical Engineering +20

YAP Regulates Hematopoietic Stem Cell Formation in Response to the Biomechanical Forces of Blood Flow

Vanessa Lundin, Wade W. Sugden, Lindsay N. Theodore, +9

Developmental Cell

MechanobiologyBiomechanical ForcesMedicineStem Cell MobilizationPhysiology +10

Signals from the surface modulate differentiation of human pluripotent stem cells through glycosaminoglycans and integrins

Paul J. Wrighton, Joseph R. Klim, Brandon Hernandez, +3

Proceedings of the National Academy of Sciences

Quantitative intravital imaging in zebrafish reveals <i>in vivo</i> dynamics of physiological-stress-induced mitophagy

Paul J. Wrighton, Arkadi Shwartz, Jin‐Mi Heo, +4

Journal of Cell Science

Fetal alcohol spectrum disorder predisposes to metabolic abnormalities in adulthood

Olivia Weeks, Gabriel D. Bossé, Isaac M. Oderberg, +15

Journal of Clinical Investigation

Metabolic DisorderFetal ComplicationObesityMetabolic SyndromeBody Composition +19

Synthetic CRISPR/Cas9 reagents facilitate genome editing and homology directed repair

Sara DiNapoli, Raúl Martinez-McFaline, Caitlin Gribbin, +13

Nucleic Acids Research

Small-Molecule-Modified Surfaces Engage Cells through the α_vβ₃ Integrin

Joseph R. Klim, Anthony J. Fowler, Adam H. Courtney, +4

ACS Chemical Biology

Overlapping Ligand SpecificityEngineeringPeptide EngineeringCell AdhesionCellular Adhesion +12

A quantitative single-cell assay for retrograde membrane traffic enables rapid detection of defects in cellular organization

Phi Luong, Qian Li, Pin-Fang Chen, +9

Molecular Biology of the Cell

Retrograde Membrane TrafficRetrograde MembraneMolecular BiologyCell CultureCytoskeleton +16