UGA is an additional glycine codon in uncultured SR1 bacteria from the human microbiota

James H. Campbell, Patrick O’Donoghue, Alisha G. Campbell, +5

Proceedings of the National Academy of Sciences

BiologySr1 BacteriaMicrobial PathogensNatural SciencesGenetics +13

Structure of pyrrolysyl-tRNA synthetase, an archaeal enzyme for genetic code innovation

Jennifer M. Kavran, Sarath Gundllapalli, Patrick O’Donoghue, +3

Proceedings of the National Academy of Sciences

Biomolecular Structure PredictionMolecular BiologyArchaeaProtein SynthesisBiosynthesis +16

RNA-dependent conversion of phosphoserine forms selenocysteine in eukaryotes and archaea

Jing Yuan, Sotiria Palioura, Juan Carlos Salazar, +6

Proceedings of the National Academy of Sciences

Pyrrolysyl-tRNA synthetase–tRNAPyl structure reveals the molecular basis of orthogonality

K. Nozawa, Patrick O’Donoghue, Sarath Gundllapalli, +5

Nature

Nucleic Acid ChemistryMolecular BiologyPyrrolysyl-trna Synthetase–trnapyl StructureMedicineStructural Biology +1

Upgrading protein synthesis for synthetic biology

Patrick O’Donoghue, Jiqiang Ling, Yane‐Shih Wang, +1

Nature Chemical Biology

BiosynthesisEngineeringNatural SciencesMolecular BiologySynthetic Biology +5

Polyspecific pyrrolysyl-tRNA synthetases from directed evolution

Li-Tao Guo, Yane‐Shih Wang, Akiyoshi Nakamura, +7

Proceedings of the National Academy of Sciences

BiosynthesisBiochemistryNatural SciencesProtein BiosynthesisDirected Evolution +9

Recoding the Genetic Code with Selenocysteine

Markus J. Bröcker, Joanne M. L. Ho, George M. Church, +2

Angewandte Chemie International Edition

Revealing the amino acid composition of proteins within an expanded genetic code

Hans R. Aerni, Mark A. Shifman, Svetlana Rogulina, +2

Nucleic Acids Research

GeneticsMolecular BiologyEscherichia ColiProtein GeneticsAmino Acid Purity +18

Near‐cognate suppression of amber, opal and quadruplet codons competes with aminoacyl‐tRNA^Pyl for genetic code expansion

Patrick O’Donoghue, Laure Prat, Ilka U. Heinemann, +4

FEBS Letters

The evolutionary history of Cys-tRNA ^Cys formation

Patrick O’Donoghue, Anurag Sethi, Carl R. Woese, +1

Proceedings of the National Academy of Sciences

BiologyPhylogeneticsBiochemistryEvolutionary HistoryNatural Sciences +13