James Holehouse

The minimal intrinsic stochasticity of constitutively expressed eukaryotic genes is sub-Poissonian

Douglas E. Weidemann, James Holehouse, Abhyudai Singh et al. · Science Advances · 2023 · 41 citations · Full text

Genetics, Cell Cycle, Gene Regulatory Network +20

Distinguishing between models of mammalian gene expression: telegraph-like models versus mechanistic models

Svitlana Braichenko, James Holehouse, Ramon Grima · Journal of The Royal Society Interface · 2021 · 36 citations · Full text

Engineering, Genetics, Gene Regulatory Network +16

Revisiting the Reduction of Stochastic Models of Genetic Feedback Loops with Fast Promoter Switching

James Holehouse, Ramon Grima · Biophysical Journal · 2019 · 29 citations · Full text

Stochastic Models, Engineering, Genetics +11

Stochastic time-dependent enzyme kinetics: Closed-form solution and transient bimodality

James Holehouse, Augustinas Sukys, Ramon Grima · The Journal of Chemical Physics · 2020 · 18 citations · Full text

Solving the time-dependent protein distributions for autoregulated bursty gene expression using spectral decomposition

Bingjie Wu, James Holehouse, Ramon Grima et al. · The Journal of Chemical Physics · 2024 · 15 citations · Full text