Overcoming the polyethylene glycol dilemma via pathological environment-sensitive change of the surface property of nanoparticles for cellular entry

Susumu Hama, Shoko Itakura, Mayumi Nakai, +4

Journal of Controlled Release

NanomedicineNanotherapeuticsEngineeringPolyethylene Glycol DilemmaBiofabrication +5

Development of nanoparticles derived from corn as mass producible bionanoparticles with anticancer activity

Daisuke Sasaki, Kosuke Kusamori, Yukiya Takayama, +3

Scientific Reports

Usefulness of Artificial Membrane, Strat-M®, in the Assessment of Drug Permeation from Complex Vehicles in Finite Dose Conditions

Florencio Arce, Narumi Asano, Gerard Lee See, +3

Pharmaceutics

Tumor Microenvironment-Sensitive Liposomes Penetrate Tumor Tissue via Attenuated Interaction of the Extracellular Matrix and Tumor Cells and Accompanying Actin Depolymerization

Satoko Suzuki, Shoko Itakura, Ryo Matsui, +5

Biomacromolecules

EngineeringAccompanying Actin DepolymerizationExtracellular MicrovesiclesCytoskeletonBiomedical Engineering +18

Prevention of tumor growth by needle-free jet injection of anti-C7orf24 siRNA

Susumu Hama, Mayumi Arata, Ibuki Nakamura, +4

Cancer Gene Therapy

Anti-c7orf24 SirnaTumor BiologyNeedle-free Jet InjectionNovel TherapyMedicine +9

Enhanced nose-to-brain delivery of tranilast using liquid crystal formulations

Gerard Lee See, Florencio Arce, Sabrina Dahlizar, +7

Journal of Controlled Release

Tissue EngineeringNanomedicineEngineeringBiomedical EngineeringDrug Delivery System +2

Rapid modification of antibodies on the surface of liposomes composed of high-affinity protein A-conjugated phospholipid for selective drug delivery

Susumu Hama, Mika Sakai, Shoko Itakura, +2

Biochemistry and Biophysics Reports

Gene knockdown in HaCaT cells by small interfering RNAs entrapped in grapefruit-derived extracellular vesicles using a microfluidic device

Shoko Itakura, Ayaka Shohji, Sayaka Amagai, +4

Scientific Reports

NanoparticlesHacat CellsEngineeringLipid NanoparticlesMolecular Biology +18

Lipocalin2 as a plasma marker for tumors with hypoxic regions

Ibuki Nakamura, Susumu Hama, Shoko Itakura, +4

Scientific Reports

PathologyCancer BiologyPlasma MarkerTumor BiologyCancer Cell Biology +15

Effective cytoplasmic release of siRNA from liposomal carriers by controlling the electrostatic interaction of siRNA with a charge-invertible peptide, in response to cytoplasmic pH

Shoko Itakura, Susumu Hama, Ryo Matsui, +1

Nanoscale