Deodial Guiadeen

1,3,8-Triazaspiro[4.5]decane-2,4-diones as Efficacious Pan-Inhibitors of Hypoxia-Inducible Factor Prolyl Hydroxylase 1–3 (HIF PHD1–3) for the Treatment of Anemia

Petr Váchal, Shouwu Miao, Joan M. Pierce et al. · Journal of Medicinal Chemistry · 2012 · 66 citations · Full text

Pharmaceutical Science, Drug Target, Efficacious Pan-inhibitors +21

Discovery of 8-Amino-imidazo[1,5-<i>a</i>]pyrazines as Reversible BTK Inhibitors for the Treatment of Rheumatoid Arthritis

Jian Liu, Deodial Guiadeen, A. D. Krikorian et al. · ACS Medicinal Chemistry Letters · 2015 · 38 citations · Full text

Drug Target, Bioorganic Chemistry, Tyrosine Kinase +23

Discovery of a Potent and Selective DGAT1 Inhibitor with a Piperidinyl-oxy-cyclohexanecarboxylic Acid Moiety

Shuwen He, Qingmei Hong, Zhong Lai et al. · ACS Medicinal Chemistry Letters · 2014 · 26 citations · Full text

Pharmacotherapy, Chemical Biology, Pharmaceutical Chemistry +22

Discovery of novel BTK inhibitors with carboxylic acids

Xiaolei Gao, James Wang, Jian Liu et al. · Bioorganic & Medicinal Chemistry Letters · 2016 · 18 citations · Full text

Medicinal Chemistry, Medicine, Drug Development +5

Potent, non-covalent reversible BTK inhibitors with 8-amino-imidazo[1,5-a]pyrazine core featuring 3-position bicyclic ring substitutes

Jian Liu, Deodial Guiadeen, A. D. Krikorian et al. · Bioorganic & Medicinal Chemistry Letters · 2020 · 16 citations · Full text

Medicinal Chemistry, Medicine, Natural Sciences +7