Ternary complexes of pDNA, polyethylenimine, and γ-polyglutamic acid for gene delivery systems

Tomoaki Kurosaki, Takashi Kitahara, Shintaro Fumoto, +7

Biomaterials

Ternary ComplexesEngineeringBiotechnologyMolecular BiologyOligonucleotide +6

Population pharmacokinetics and pharmacodynamics of linezolid‐induced thrombocytopenia in hospitalized patients

Yasuhiro Tsuji, Nicholas H. G. Holford, Hidefumi Kasai, +6

British Journal of Clinical Pharmacology

The development of a gene vector electrostatically assembled with a polysaccharide capsule

Tomoaki Kurosaki, Takashi Kitahara, Shigeru Kawakami, +7

Biomaterials

Polysaccharide CapsuleCell-based Drug DeliveryEngineeringBioconjugationSynthetic Biology +4

An artificial neural network−pharmacokinetic model and its interpretation using Shapley additive explanations

Chika Ogami, Yasuhiro Tsuji, Hiroto Seki, +4

CPT Pharmacometrics & Systems Pharmacology

Artificial IntelligenceEngineeringMachine LearningPharmacokineticsPharmacodynamic Modeling +19

Influence of Feeding Schedule on 24-h Rhythm of Hepatotoxicity Induced by Acetaminophen in Mice

Naoya Matsunaga, Naomi Nakamura, Noriyo Yoneda, +5

Journal of Pharmacology and Experimental Therapeutics

Methotrexate Chronotherapy is Effective Against Rheumatoid Arthritis

Hideto To, Hiromichi Yoshimatsu, Mari Tomonari, +12

Chronobiology International

Immune RegulationImmunologyImmune SystemPsoriatic ArthritisInflammatory Arthritis +17

Population‐Based Investigation of Valproic Acid Relative Clearance Using Nonlinear Mixed Effects Modeling: Influence of Drug‐Drug Interaction and Patient Characteristics

Eiji Yukawa, Hideto To, Shigehiro Ohdo, +2

The Journal of Clinical Pharmacology

Electrophysiological Characterization of Tight Junctional Pathway of Rabbit Cornea Treated with Ophthalmic Ingredients

Tadahiro Nakamura, Mikiko Yamada, Mugen Teshima, +4

Biological and Pharmaceutical Bulletin

Rabbit Cornea TreatedOcular Surface PhysiologyOcular PharmacologyOptogeneticsCorneal Permeability +16

Circadian Clock in a Mouse Colon Tumor Regulates Intracellular Iron Levels to Promote Tumor Progression

Fumiyasu Okazaki, Naoya Matsunaga, Hiroyuki Okazaki, +14

Journal of Biological Chemistry

Chronobiological disturbances with hyperthermia and hypercortisolism induced by chronic mild stress in rats

Kimio Ushijima, T. Morikawa, Hideto To, +2

Behavioural Brain Research

Chronobiological DisturbancesPsychoneuroimmunologyHyperthermiaStress HormoneStress +8