Synthesis, monoamine oxidase inhibition activity and molecular docking studies of novel 4-hydroxy-N′-[benzylidene or 1-phenylethylidene]-2-H/methyl/benzyl-1,2-benzothiazine-3-carbohydrazide 1,1-dioxides

Furqan Ahmad Saddique, Sumera Zaib, Saquib Jalil, +6

European Journal of Medicinal Chemistry

Medicinal ChemistryBiochemistryNatural SciencesMedicineOrganic Chemistry +5

Synthesis, biological evaluation, and docking studies of new raloxifene sulfonate or sulfamate derivatives as inhibitors of nucleotide pyrophosphatase/phosphodiesterase

Mohammed I. El–Gamal, Saif Ullah, Seyed–Omar Zaraei, +8

European Journal of Medicinal Chemistry

Medicinal ChemistryPharmaceutical ScienceBiochemistryAntiparasitic AgentNatural Sciences +10

Semicarbazones, thiosemicarbazone, thiazole and oxazole analogues as monoamine oxidase inhibitors: Synthesis, characterization, biological evaluation, molecular docking, and kinetic studies

Syeda Uroos Qazi, Asia Naz, Abdul Hameed, +5

Bioorganic Chemistry

Medicinal ChemistryBiochemistryMonoamine Oxidase InhibitorsMedicineNatural Sciences +8

Deep eutectic solvent mediated synthesis of 3,4-dihydropyrimidin-2(1H)-ones and evaluation of biological activities targeting neurodegenerative disorders

Maria Saleem Khan, Muhammad Asif Nawaz, Saquib Jalil, +8

Bioorganic Chemistry

Combinatorial ChemistryNeurodegenerative DiseasesBiochemistryMedicinePharmacological Agent +6

Synthesis, characterization, monoamine oxidase inhibition, molecular docking and dynamic simulations of novel 2,1-benzothiazine-2,2-dioxide derivatives

Shakeel Ahmad, Sumera Zaib, Saquib Jalil, +6

Bioorganic Chemistry

Combinatorial ChemistryMedicinal ChemistryBiochemistryMedicineNatural Sciences +8

Synthesis, biological evaluation, and molecular docking study of sulfonate derivatives as nucleotide pyrophosphatase/phosphodiesterase (NPP) inhibitors

Mohammad H. Semreen, Mohammed I. El‐Gamal, Saif Ullah, +6

Bioorganic & Medicinal Chemistry

Inhibitory ActivityMedicinal ChemistryPharmaceutical ScienceBiochemistryNatural Sciences +10

Therapeutic potential of 1,3,4-oxadiazoles as potential lead compounds for the treatment of Alzheimer's disease

Saira Naseem, Ahmed Temirak, Aqeel Imran, +6

RSC Advances

Quinoline–sulfonamides as a multi-targeting neurotherapeutic for cognitive decline: <i>in vitro</i> , <i>in silico</i> studies and ADME evaluation of monoamine oxidases and cholinesterases inhibitors

Saquib Jalil, Zahid Hussain, Syed Mobashir Ali Abid, +2

RSC Advances

Deep learning-based prediction of inhibitors interaction with Butyrylcholinesterase for the treatment of Alzheimer's disease

Farah Jabeen, Zia Ur Rehman, Sajid Shah, +5

Computers & Electrical Engineering

Drug TargetAlzheimer's DiseaseMedicineDementiaRational Drug Design +9

Synthesis and Evaluation of Novel S-alkyl Phthalimide- and S-benzyl-oxadiazole-quinoline Hybrids as Inhibitors of Monoamine Oxidase and Acetylcholinesterase

Bilal Ahmad Khan, Syeda Shamila Hamdani, Saquib Jalil, +7

Pharmaceuticals