Embryonic death of Mek1-deficient mice reveals a role for this kinase in angiogenesis in the labyrinthine region of the placenta

Sylvie Giroux, Michel G. Tremblay, Dominic Bernard, +8

Current Biology

Developmental BiologyAngiogenesisPlacental DevelopmentCell DeathMek1-deficient Mice +8

Early Postnatal Lethality inHoxa-5Mutant Mice Is Attributable to Respiratory Tract Defects

Josée Aubin, Margot Lemieux, Michel G. Tremblay, +2

Developmental Biology

Acute Lung InjuryKnockout MouseDevelopmental BiologyAllergyLung Inflammation +6

<i>Mek2</i> Is Dispensable for Mouse Growth and Development

Louis-François Bélanger, Sophie Roy, Michel G. Tremblay, +6

Molecular and Cellular Biology

Cell GrowthMouse GrowthCellular PhysiologyMek1 GeneTissue Development +14

Overexpression of seleno-glutathione peroxidase by gene transfer enhances the resistance of T47D human breast cells to clastogenic oxidants.

Marc-Édouard Mirault, Angelo Tremblay, Nathalie Beaudoin, +1

Journal of Biological Chemistry

Dna DamageSeleno-glutathione PeroxidaseDna BreakageLipid PeroxidationCell Death +15

Conditional Inactivation of Upstream Binding Factor Reveals Its Epigenetic Functions and the Existence of a Somatic Nucleolar Precursor Body

Nourdine Hamdane, Victor Y. Stefanovsky, Michel G. Tremblay, +6

PLoS Genetics

Ribosomal RnaEpigenetic ChangeGeneticsEpigenetic FunctionsEpigenetics +23

A unique enhancer boundary complex on the mouse ribosomal RNA genes persists after loss of Rrn3 or UBF and the inactivation of RNA polymerase I transcription

Chelsea Herdman, Jean-Clément Mars, Victor Y. Stefanovsky, +5

PLoS Genetics

Histone ModificationsGeneticsMolecular BiologyEpigeneticsTranscriptional Regulation +16

The chemotherapeutic agent CX-5461 irreversibly blocks RNA polymerase I initiation and promoter release to cause nucleolar disruption, DNA damage and cell inviability

Jean-Clément Mars, Michel G. Tremblay, Mélissa Valere, +4

NAR Cancer

Relative resistance to chlorine of poliovirus and coxsackievirus isolates from environmental sources and drinking water

Pierre Payment, Michel G. Tremblay, M. Trudel

Applied and Environmental Microbiology

Drinking WaterEnvironmental IsolatesFree Residual ChlorineRelative ResistanceGastrointestinal Virus +10

Extended-Synaptotagmin-2 Mediates FGF Receptor Endocytosis and ERK Activation In Vivo

Steve Jean, Alexander Mikryukov, Michel G. Tremblay, +4

Developmental Cell

Developmental BiologySignal TransductionSignaling PathwayReceptor Tyrosine KinaseAutophagy +9

Binding of HIV-1 to Its Receptor Induces Tyrosine Phosphorylation of Several CD4-Associated Proteins, Including the Phosphatidylinositol 3-Kinase

Guylaine Briand, Benoı̂t Barbeau, Michel G. Tremblay

Virology

Signal TransductionReceptor Tyrosine KinaseHuman RetrovirusImmunologyAntiviral Response +7