John R. Lakanen

The role of hypusine depletion in cytostasis induced by <i>S</i>-adenosyl-<scp>l</scp>-methionine decarboxylase inhibition: new evidence provided by 1-methylspermidine and 1,12-dimethylspermine

T L Byers, John R. Lakanen, James K. Coward et al. · Biochemical Journal · 1994 · 73 citations · Full text

Life Sciences, Biochemistry, Pharmacology +7

.alpha.-Methyl polyamines: metabolically stable spermidine and spermine mimics capable of supporting growth in cells depleted of polyamines

John R. Lakanen, James K. Coward, Anthony E. Pegg · Journal of Medicinal Chemistry · 1992 · 64 citations

Pharmacy, Pharmacology, Drug Design +5

Enhancement of the spermidine uptake system and lethal effects of spermidine overaccumulation in ornithine decarboxylase-overproducing L1210 cells under hyposmotic stress.

R. Poulin, James K. Coward, John R. Lakanen et al. · Journal of Biological Chemistry · 1993 · 57 citations · Full text

Life Sciences, Biochemistry, Cell Biology +7

Synthesis and Biochemical Evaluation of Adenosylspermidine, a Nucleoside-Polyamine Adduct Inhibitor of Spermidine Synthase

John R. Lakanen, Anthony E. Pegg, James K. Coward · Journal of Medicinal Chemistry · 1995 · 30 citations · Full text

Medicine, Molecular Biology, Pharmacology +6

Thermally stable allylzirconium halide compounds. Synthesis, crystal structure, and dynamics of (.eta.5-C5Me5)(.eta.3-1,2,3-trimethylallyl)ZrBr2 and (.eta.5-C5Me5)(.eta.3-1,1,2-trimethylallyl)ZrBr2

Erlund J. Larson, Paul C. Van Dort, James S. Dailey et al. · Organometallics · 1987 · 17 citations

Natural Sciences, Chemistry, Materials Science +7