Sébastien Debarge

Chemoenzymatic Asymmetric Synthesis of Pregabalin Precursors via Asymmetric Bioreduction of β-Cyanoacrylate Esters Using Ene-Reductases

Christoph K. Winkler, Dorina Clay, Simon B. Davies et al. · The Journal of Organic Chemistry · 2013 · 89 citations · Full text

Engineering, Organic Chemistry, Pregabalin Precursors +16

Evaluation of Several Routes to Advanced Pregabalin Intermediates: Synthesis and Enantioselective Enzymatic Reduction Using Ene-Reductases

Sébastien Debarge, Paul McDaid, P.M. O'Neill et al. · Organic Process Research & Development · 2013 · 45 citations

Bioorganic Chemistry, Advanced Pregabalin, Engineering +16

Nitrile as Activating Group in the Asymmetric Bioreduction of β‐Cyanoacrylic Acids Catalyzed by Ene‐Reductases

Christoph K. Winkler, Dorina Clay, Nikolaus G. Turrini et al. · Advanced Synthesis & Catalysis · 2014 · 33 citations · Full text

Rearrangement or gem-difluorination of quinine and 9-epiquinine and their acetates in superacid

Sébastien Debarge, Sébastien Thibaudeau, Bruno Violeau et al. · Tetrahedron · 2005 · 29 citations

Bioorganic Chemistry, Engineering, Biochemistry +7

Design and Synthesis of α-Carboxy Phosphononucleosides

Sébastien Debarge, Jan Balzarini, Anita R. Maguire · The Journal of Organic Chemistry · 2010 · 28 citations · Full text

Bioorganic Chemistry, Organic Chemistry, Novel Phosphononucleosides +17