Chikau Fujio

Transfer of the E. coli O6-methyltransferase gene into repair-deficient human cells and restoration of cellular resistance to N-methyl-N′-nitro-N-nitrosoguanidine

Kanji Ishizaki, Tohru Tsujimura, Hideo Yawata et al. · Mutation Research/DNA Repair Reports · 1986 · 66 citations

Repair-deficient Human Cells, Reactive Nitrogen Specie, Natural Sciences +10

O6-methylguanine methyltransferase activity and sensitivity of Japanese tumor cell strains to 1-(4-amino-2-methyl-5-pyrimidinyl)methyl-3-(2-chloroethyl)- 3-nitrosourea hydrochloride.

Tohru Tsujimura, Y P Zhang, Chikau Fujio et al. · PubMed · 1987 · 31 citations

Cancer Research, Biochemistry, Oncogenic Agent +14

Expression of the truncated E. coliO6-methylguanine methyltransferase gene in repair-deficient human cells and restoration of cellular resistance to alkylating agents

Kanji Ishizaki, Tohru Tsujimura, Chikau Fujio et al. · Mutation Research/DNA Repair Reports · 1987 · 29 citations

Repair-deficient Human Cells, Epigenetic Change, Genetics +6

Comparative analysis of O6-methylguanine methyltransferase activity and cellular sensitivity to alkylating agents in cell strains derived from a variety of animal species

Mituo Ikenaga, Tohru Tsujimura, Chikau Fujio et al. · Mutation Research/DNA Repair Reports · 1987 · 28 citations

Biotransformation, Aldehyde Dehydrogenase, Biochemistry +14

Hypersensitivity of human tumor xenografts lacking <i>O</i>⁶-alkylguanine-DNA alkyltransferase to the anti-tumor agent 1-(4-amino-2-methyl-5-pyrimidinyl)methyl-3-(2-chloroethyl)-3-nitrosourea

Chikau Fujio, Hae Ryong Chang, Tohru Tsujimura et al. · Carcinogenesis · 1989 · 24 citations