A selective inhibitor reveals PI3Kγ dependence of TH17 cell differentiation

Giovanna Bergamini, Kathryn M. Bell, Satoko Shimamura, +22

Nature Chemical Biology

Signal TransductionSignaling PathwayCell RegulationMolecular RegulationTh17 Cell Differentiation +5

A monoclonal antibody to recombinant human IFN-alpha receptor inhibits biologic activity of several species of human IFN-alpha, IFN-beta, and IFN-omega. Detection of heterogeneity of the cellular type I IFN receptor

Pierre Benoit, Deborah Maguire, Ivan Plavec, +3

The Journal of Immunology

RevM10-expressing T cells derived in vivo from transduced human hematopoietic stem-progenitor cells inhibit human immunodeficiency virus replication

Mark Bonyhadi, Katherine G. Moss, A Voytovich, +7

Journal of Virology

Cell TherapyT-regulatory CellImmunologyRevm10-expressing T CellsImmunotherapy +16

A Novel Human Amphotropic Packaging Cell Line: High Titer, Complement Resistance, and Improved Safety

Richard Rigg, Jingyi Chen, Jonathan Dando, +3

Virology

Regenerative MedicineTissue EngineeringEngineeringComplement ResistanceMedicine +7

Scaffold Attachment Region-Mediated Enhancement of Retroviral Vector Expression in Primary T Cells

Manju Agarwal, Timothy W. Austin, Franck Morel, +3

Journal of Virology

An integrative biology approach for analysis of drug action in models of human vascular inflammation

Eric J. Kunkel, Marlene Dea, Allen Ebens, +9

The FASEB Journal

Drug ActivitiesImmunologyDrug ActionPharmacotherapyInflammation +17

Rapid Structure-Activity and Selectivity Analysis of Kinase Inhibitors by BioMAP Analysis in Complex Human Primary Cell-Based Models

Eric J. Kunkel, Ivan Plavec, Dat Nguyen, +10

Assay and Drug Development Technologies

Drug TargetEngineeringKinase InhibitorsComplex SystemsSelectivity Analysis +15

Construction and Molecular Analysis of Gene Transfer Systems Derived from Bovine Immunodeficiency Virus

Robert D. Berkowitz, Heini Ilves, WeiYu Lin, +5

Journal of Virology

Viral ReplicationSynthetic VirologyImmunologyMolecular BiologyGene Transfer Systems +17

High transdominant RevM10 protein levels are required to inhibit HIV-1 replication in cell lines and primary T cells: implication for gene therapy of AIDS

Ivan Plavec, Manju Agarwal, KE Ho, +7

Gene Therapy

Viral ReplicationHuman RetrovirusImmunologyAntiviral ResponseCell Lines +7

Human Beta Interferon Scaffold Attachment Region Inhibits De Novo Methylation and Confers Long-Term, Copy Number-Dependent Expression to a Retroviral Vector

Qi Dang, Jennifer Auten, Ivan Plavec

Journal of Virology