Mutational heterogeneity in cancer and the search for new cancer-associated genes

Michael S. Lawrence, Petar Stojanov, Paz Polak, +62

Nature

Cell-of-origin chromatin organization shapes the mutational landscape of cancer

Paz Polak, Rosa Karlić, Amnon Koren, +8

Nature

Whole-Genome Sequencing in Autism Identifies Hot Spots for De Novo Germline Mutation

Jacob J. Michaelson, Yujian Shi, Madhusudan Gujral, +25

Cell

Whole-genome SequencingSequencingSyndromic AutismNext-generation SequencingGenetics +7

Mutational Strand Asymmetries in Cancer Genomes Reveal Mechanisms of DNA Damage and Repair

Nicholas J. Haradhvala, Paz Polak, Petar Stojanov, +13

Cell

ChromatinGenome InstabilityDna DamageMutational Strand AsymmetriesSomatic Variant +6

Genome-wide patterns and properties of de novo mutations in humans

Laurent C. Francioli, Paz Polak, Amnon Koren, +15

Nature Genetics

Allelic VariantSomatic VariantGenetic DisorderGenome-wide PatternsGenetics +5

Differential Relationship of DNA Replication Timing to Different Forms of Human Mutation and Variation

Amnon Koren, Paz Polak, James Nemesh, +4

The American Journal of Human Genetics

BiologyGenome InstabilityDna SequencingMutation-based TestingMedicine +11

T cell help controls the speed of the cell cycle in germinal center B cells

Alexander D. Gitlin, Christian T. Mayer, Thiago Y. Oliveira, +4

Science

ChromatinT Cell HelpDevelopmental BiologyCell RegulationCell Division +10

Genetic Variation in Human DNA Replication Timing

Amnon Koren, Robert E. Handsaker, Nolan Kamitaki, +5

Cell

Genome InstabilityDna SequencingGeneticsDna AnalysisDna Replication +2

Analysis of somatic microsatellite indels identifies driver events in human tumors

Yosef E. Maruvka, Kent W. Mouw, Rosa Karlić, +15

Nature Biotechnology

Human TumorsTumor BiologySomatic VariantTumor HeterogeneityGenetics +5

<i>ELG1</i> , a yeast gene required for genome stability, forms a complex related to replication factor C

Shay Ben‐Aroya, Amnon Koren, Batia Liefshitz, +2

Proceedings of the National Academy of Sciences