Yoshihito Kasanami

Cav3.2 overexpression in L4 dorsal root ganglion neurons after L5 spinal nerve cutting involves Egr-1, USP5 and HMGB1 in rats: An emerging signaling pathway for neuropathic pain

Shiori Tomita, Fumiko Sekiguchi, Yoshihito Kasanami et al. · European Journal of Pharmacology · 2020 · 30 citations

L5 Spinal Nerve, Spinal Cord Injury, Molecular Neuroscience +13

Design and synthesis of novel anti-hyperalgesic agents based on 6-prenylnaringenin as the T-type calcium channel blockers

Huy Du Nguyen, Takuya Okada, Shun Kitamura et al. · Bioorganic & Medicinal Chemistry · 2018 · 20 citations · Full text

Pharmaceutical Science, Pain Medicine, Medicine +7

Genetic deletion of Cav3.2 T-type calcium channels abolishes H2S-dependent somatic and visceral pain signaling in C57BL/6 mice

Kazuki Matsui, Maho Tsubota, Saaya Fukushi et al. · Journal of Pharmacological Sciences · 2019 · 16 citations · Full text

A hydrolysate of poly-trans-[(2-carboxyethyl)germasesquioxane] (Ge-132) suppresses Cav3.2-dependent pain by sequestering exogenous and endogenous sulfide

Fumiko Sekiguchi, Nene Koike, Yasuhiro Shimada et al. · Redox Biology · 2022 · 12 citations · Full text

Discovery of pimozide derivatives as novel T-type calcium channel inhibitors with little binding affinity to dopamine D2 receptors for treatment of somatic and visceral pain

Yoshihito Kasanami, Chihiro Ishikawa, Takahiro Kino et al. · European Journal of Medicinal Chemistry · 2022 · 10 citations · Full text

Medicinal Chemistry, Visceral Pain, Pimozide Derivatives +13