Haiju Geng

Discovery and Optimization of Chromeno[2,3-<i>c</i>]pyrrol-9(2<i>H</i>)-ones as Novel Selective and Orally Bioavailable Phosphodiesterase 5 Inhibitors for the Treatment of Pulmonary Arterial Hypertension

Deyan Wu, Tianhua Zhang, Yiping Chen et al. · Journal of Medicinal Chemistry · 2017 · 40 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Optimization of Chromeno[2,3-<i>c</i>]pyrrol-9(2<i>H</i>)-ones as Highly Potent, Selective, and Orally Bioavailable PDE5 Inhibitors: Structure–Activity Relationship, X-ray Crystal Structure, and Pharmacodynamic Effect on Pulmonary Arterial Hypertension

Deyan Wu, Ya-Dan Huang, Yiping Chen et al. · Journal of Medicinal Chemistry · 2018 · 28 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Discovery of Potent, Selective, and Orally Bioavailable Inhibitors against Phosphodiesterase-9, a Novel Target for the Treatment of Vascular Dementia

Yinuo Wu, Qian Zhou, Tianhua Zhang et al. · Journal of Medicinal Chemistry · 2019 · 22 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17