Neurological Manifestations of COVID-19 Feature T Cell Exhaustion and Dedifferentiated Monocytes in Cerebrospinal Fluid

Michael Heming, Xiaolin Li, Saskia Räuber, +15

Immunity

Dedifferentiated MonocytesNeurovirologyMedicineCerebrospinal FluidImmunology +7

Single-cell profiling of CNS border compartment leukocytes reveals that B cells and their progenitors reside in non-diseased meninges

David Schafflick, Jolien Wolbert, Michael Heming, +16

Nature Neuroscience

Human CellImmune Cell DevelopmentMedicineImmunologyB Cells +7

Early intervention with 3BNC117 and romidepsin at antiretroviral treatment initiation in people with HIV-1: a phase 1b/2a, randomized trial

Jesper Damsgaard Gunst, Marie H. Pahus, Míriam Rosás-Umbert, +30

Nature Medicine

Hiv/aids CounsellingTreatment And PreventionHuman RetrovirusPharmacologyAntiviral Therapy +7

A single-cell analysis framework allows for characterization of CSF leukocytes and their tissue of origin in multiple sclerosis

Patrick Ostkamp, Marie Deffner, Andreas Schulte‐Mecklenbeck, +12

Science Translational Medicine

High Frequencies of Polyfunctional CD8⁺NK Cells in Chronic HIV-1 Infection Are Associated with Slower Disease Progression

Fareed Ahmad, Henoch S. Hong, Marc Jäckel, +9

Journal of Virology

Identification of a CD4 T-cell epitope in the hemagglutinin stalk domain of pandemic H1N1 influenza virus and its antigen-driven TCR usage signature in BALB/c mice

I‐Na Lu, Sophie Farinelle, Aurélie Sausy, +1

Cellular and Molecular Immunology

Tumor-associated hematopoietic stem and progenitor cells positively linked to glioblastoma progression

I‐Na Lu, Celia Dobersalske, Laurèl Rauschenbach, +12

Nature Communications

FcγRIII (CD16)‐mediated ADCC by NK cells is regulated by monocytes and FcγRII (CD32)

Nupur Bhatnagar, Fareed Ahmad, Henoch S. Hong, +5

European Journal of Immunology

Adaptive Immune SystemImmunologyImmune RegulationImmunodominanceNk Cells +19

Intratumor heterogeneity and T cell exhaustion in primary CNS lymphoma

Michael Heming, Svea Haessner, Jolien Wolbert, +16

Genome Medicine

A virus-like particle vaccine candidate for influenza A virus based on multiple conserved antigens presented on hepatitis B tandem core particles

Alejandro Ramirez, Stephen Morris, Sophie Maucourant, +7

Vaccine

VaccinationCross-protectionVaccine TargetImmunologyVirology +7