Cryopreserved mesenchymal stromal cells display impaired immunosuppressive properties as a result of heat-shock response and impaired interferon-γ licensing

Moïra François, Ian B. Copland, Shala Yuan, +3

Cytotherapy

Cell TherapyImmune Cell DevelopmentMedicineImmune RegulationImmunology +11

IDO-Independent Suppression of T Cell Effector Function by IFN-γ–Licensed Human Mesenchymal Stromal Cells

Raghavan Chinnadurai, Ian B. Copland, Seema R. Patel, +1

The Journal of Immunology

Ifn-γ MscsImmunologyImmune RegulationImmunologic MechanismImmunotherapeutics +17

Cryopreserved Mesenchymal Stromal Cells Are Susceptible to T-Cell Mediated Apoptosis Which Is Partly Rescued by IFNγ Licensing

Raghavan Chinnadurai, Ian B. Copland, Marco Garcia, +4

Stem Cells

Cell TherapyImmunologyImmune RegulationCell DeathStem Cells 2016 +15

Early Changes in Lung Gene Expression due to High Tidal Volume

Ian B. Copland, Brian P. Kavanagh, Doreen Engelberts, +3

American Journal of Respiratory and Critical Care Medicine

Actin Cytoskeletal Disruption following Cryopreservation Alters the Biodistribution of Human Mesenchymal Stromal Cells In Vivo

Raghavan Chinnadurai, Marco Garcia, Yumiko Sakurai, +4

Stem Cell Reports

Opposing Effects of 60% Oxygen and Neutrophil Influx on Alveologenesis in the Neonatal Rat

Yi Man, Robert P. Jankov, Rosetta Belcastro, +8

American Journal of Respiratory and Critical Care Medicine

AsthmaAcute Lung InjuryInflammatory Lung DiseaseLung InflammationImmunology +18

High Tidal Volume Ventilation Causes Different Inflammatory Responses in Newborn versus Adult Lung

Ian B. Copland, Francisco Eulógio Martinez, Brian P. Kavanagh, +4

American Journal of Respiratory and Critical Care Medicine

The safety of autologous and metabolically fit bone marrow mesenchymal stromal cells in medically refractory Crohn's disease – a phase 1 trial with three doses

Tanvi Dhere, Ian B. Copland, Marco Garcia, +5

Alimentary Pharmacology & Therapeutics

Mechanical stretch-induced serotonin release from pulmonary neuroendocrine cells: implications for lung development

Jie Pan, Ian B. Copland, Martin Post, +2

American Journal of Physiology-Lung Cellular and Molecular Physiology

EngineeringPulmonary Neuroendocrine CellsLung InflammationCyclic StretchCytoskeleton +20

Human platelet lysate stimulates high-passage and senescent human multipotent mesenchymal stromal cell growth and rejuvenation in vitro

Sarah Griffiths, Priya R. Baraniak, Ian B. Copland, +2

Cytotherapy

Regenerative MedicineThrombopoiesisBlood PlateletMedicineStem Cell Research +7