Triiodothyronine induces UCP-1 expression and mitochondrial biogenesis in human adipocytes

Joo‐Young Lee, Nobuyuki Takahashi, Midori Yasubuchi, +6

American Journal of Physiology-Cell Physiology

Metabolic RemodelingOxidative StressMetabolic SyndromeTranscriptional RegulationMitochondrial Biogenesis +18

Macrophage infiltration into obese adipose tissues suppresses the induction of UCP1 level in mice

Tomoya Sakamoto, Takahiro Nitta, Koji Maruno, +6

American Journal of Physiology-Endocrinology and Metabolism

Metabolic DisorderImmunologyObese Adipose TissuesMetabolic RemodelingInflammation +20

A Critical Role for Estrogen-Related Receptor Signaling in Cardiac Maturation

Tomoya Sakamoto, Timothy Matsuura, Shibiao Wan, +9

Circulation Research

Inflammation induced by RAW macrophages suppresses <i>UCP1</i> mRNA induction via ERK activation in 10T1/2 adipocytes

Tomoya Sakamoto, Nobuyuki Takahashi, Yuri Sawaragi, +4

American Journal of Physiology-Cell Physiology

Immune RegulationImmunologyMetabolic RemodelingAdipokinesCellular Physiology +25

Proinflammatory cytokine interleukin-1β suppresses cold-induced thermogenesis in adipocytes

Tsuyoshi Goto, Supaporn Naknukool, Rieko Yoshitake, +12

Cytokine

InflammationMetabolic SyndromePhysiologyImmunologyChronic Inflammation +5

Bixin regulates mRNA expression involved in adipogenesis and enhances insulin sensitivity in 3T3-L1 adipocytes through PPARγ activation

Nobuyuki Takahashi, Tsuyoshi Goto, Aki Taimatsu, +9

Biochemical and Biophysical Research Communications

Energy HomeostasisTranscriptional RegulationMrna ExpressionSignal Transduction3T3-l1 Adipocytes +10

Dehydroabietic acid, a diterpene, improves diabetes and hyperlipidemia in obese diabetic KK‐Ay mice

Min‐Sook Kang, Shizuka Hirai, Tsuyoshi Goto, +10

BioFactors

Bixin Activates PPARα and Improves Obesity-Induced Abnormalities of Carbohydrate and Lipid Metabolism in Mice

Tsuyoshi Goto, Nobuyuki Takahashi, Sota Kato, +12

Journal of Agricultural and Food Chemistry

Pparα Target GenesOxidative StressObesityMetabolic SyndromeObesity-induced Abnormalities +16

Farnesyl pyrophosphate regulates adipocyte functions as an endogenous PPARγ agonist

Tsuyoshi Goto, Hiroyuki Nagai, Kahori Egawa, +10

Biochemical Journal

Activation of peroxisome proliferator-activated receptor-α enhances fatty acid oxidation in human adipocytes

Jooyoung Lee, Hikari Hashizaki, Tsuyoshi Goto, +3

Biochemical and Biophysical Research Communications

BiochemistryMedicinePhysiologyMetabolic RegulationMetabolism +6