Adam Rolt

Vitamin E treatment in NAFLD patients demonstrates that oxidative stress drives steatosis through upregulation of de-novo lipogenesis

Maren C. Podszun, Ahmad S. Alawad, Shilpa Lingala et al. · Redox Biology · 2020 · 104 citations · Full text

Discovery, Optimization, and Characterization of Novel Chlorcyclizine Derivatives for the Treatment of Hepatitis C Virus Infection

Shanshan He, Jingbo Xiao, Andrés E. Dulcey et al. · Journal of Medicinal Chemistry · 2015 · 34 citations

Medicinal Chemistry, Hepatitis C Virus, Viral Hepatitis +15

Optimisation of a screening platform for determining IL-6 inflammatory signalling in the senescence-associated secretory phenotype (SASP)

Adam Rolt, Anitha Nair, Lynne S. Cox · Biogerontology · 2019 · 27 citations · Full text

Immunology, Cell Death, Immunologic Mechanism +18

Chlorcyclizine Inhibits Viral Fusion of Hepatitis C Virus Entry by Directly Targeting HCV Envelope Glycoprotein 1

Zongyi Hu, Adam Rolt, Xin Hu et al. · Cell chemical biology · 2020 · 24 citations · Full text

Hepatology, Viral Hepatitis, Medicine +8

Synthesis of MeBmt and related derivatives <i>via</i> syn-selective ATH-DKR

Adam Rolt, Paul M. O’Neill, T. Jake Liang et al. · RSC Advances · 2019 · 14 citations · Full text

Medicinal Chemistry, Unusual α-Amino, Derivatives +14