Efficacy and safety of a CXCR2 antagonist, AZD5069, in patients with uncontrolled persistent asthma: a randomised, double-blind, placebo-controlled trial

Paul M. O’Byrne, Hristo Metev, Margareta Puu, +6

The Lancet Respiratory Medicine

AsthmaCxcr2 AntagonistAllergyUncontrolled Persistent AsthmaClinical Trials +5

Resolvin D1 and Aspirin-Triggered Resolvin D1 Promote Resolution of Allergic Airways Responses

Alexandre de Paula Rogério, Oliver Haworth, Roxanne H. Croze, +7

The Journal of Immunology

Aspirin-triggered resolvin D1 reduces mucosal inflammation and promotes resolution in a murine model of acute lung injury

Olaf Eickmeier, Hiroyuki Seki, Oliver Haworth, +7

Mucosal Immunology

Blocking elevated p38 MAPK restores efferocytosis and inflammatory resolution in the elderly

Roel P. H. De Maeyer, Rachel C. van de Merwe, Rikah Louie, +6

Nature Immunology

InflammationAnti-inflammatoryAutoimmune DiseaseMedicineAutophagy +8

Serum amyloid A opposes lipoxin A₄to mediate glucocorticoid refractory lung inflammation in chronic obstructive pulmonary disease

Steven Bozinovski, Mohib Uddin, Ross Vlahos, +8

Proceedings of the National Academy of Sciences

InflammationAsthmaGc Refractory InflammationInflammatory Lung DiseaseLung Inflammation +11

Prosurvival activity for airway neutrophils in severe asthma

Mohib Uddin, Guangmin Nong, Jonathan Ward, +6

Thorax

Dissociation between respiratory burst activity and deoxyglucose uptake in human neutrophil granulocytes: implications for interpretation of (18)F-FDG PET images.

Hazel A. Jones, Karen A. Cadwallader, Jessica F White, +3

PubMed

Lovastatin decreases acute mucosal inflammation via 15-epi-lipoxin A4

Anna Planagumà, Michael A. Pfeffer, George Rubin, +4

Mucosal Immunology

InflammationAnti-inflammatoryAcute Mucosal InflammationImmunologyChronic Inflammation +3

Neutrophil extracellular trap formation and extracellular DNA in sputum of stable COPD patients

Frauke Pedersen, Sebastian Marwitz, Olaf Holz, +8

Respiratory Medicine

GranulocyteImmunologyPathologyStable Copd PatientsExtracellular Dna +2

Urinary Leukotriene E ₄ and Prostaglandin D ₂ Metabolites Increase in Adult and Childhood Severe Asthma Characterized by Type 2 Inflammation. A Clinical Observational Study

Johan Kolmert, Cristina Gómez, David Balgoma, +200

American Journal of Respiratory and Critical Care Medicine