IL-33 activates tumor stroma to promote intestinal polyposis

Rebecca L. Maywald, Stephanie K. Doerner, Luca Pastorelli, +10

Proceedings of the National Academy of Sciences

Human and mouse essentiality screens as a resource for disease gene discovery

Pilar Cacheiro, Violeta Muñoz‐Fuentes, Stephen A. Murray, +193

Nature Communications

Comparative analysis of single-stranded DNA donors to generate conditional null mouse alleles

Denise G. Lanza, Angelina Gaspero, Isabel Lorenzo, +12

BMC Biology

Extensive identification of genes involved in congenital and structural heart disorders and cardiomyopathy

Nadine Spielmann, Gregor Miller, Tudor I. Oprea, +243

Nature Cardiovascular Research

Cardiac MuscleHeart FailureEngineeringGeneticsMolecular Genetics +19

Characterization of mammary cancer stem cells in the MMTV-PyMT mouse model

Jun Ma, Denise G. Lanza, Ian Guest, +4

Tumor Biology

COPB2 loss of function causes a coatopathy with osteoporosis and developmental delay

Ronit Marom, Lindsay C. Burrage, Rossella Venditti, +50

The American Journal of Human Genetics

Bone DiseaseDevelopmental BiologyBone Morphogenic ProteinPhysiologyCopb2 Loss +3

Bi-allelic Variants in TONSL Cause SPONASTRIME Dysplasia and a Spectrum of Skeletal Dysplasia Phenotypes

Lindsay C. Burrage, John J. Reynolds, Nissan Baratang, +255

The American Journal of Human Genetics

Allelic VariantGenetic DisorderGeneticsBi-allelic VariantsPathology +6

CRISPR/Cas9-mediated deletion of lncRNA Gm26878 in the distant Foxf1 enhancer region

Przemysław Szafrański, Justyna A. Karolak, Denise G. Lanza, +3

Mammalian Genome

GeneticsMolecular GeneticsGene EditingCrisprGene Expression +6

Testicular germ cell tumors arise in the absence of sex-specific differentiation

Nicholas J. Webster, Rebecca L. Maywald, Susan M. Benton, +6

Development

Whole genome analysis for 163 gRNAs in Cas9-edited mice reveals minimal off-target activity

Kevin A. Peterson, Sam Khalouei, Nour Hanafi, +13

Communications Biology