Fever, sickness behavior, and expression of inflammatory genes in the hypothalamus after systemic and localized subcutaneous stimulation of rats with the toll-like receptor 7 agonist imiquimod

Jelena Damm, Florian Wiegand, Lois M. Harden, +3

Neuroscience

InflammationToll-like ReceptorsPsychoneuroimmunologyAutoimmune DiseaseMedicine +11

The transcription factor nuclear factor interleukin 6 mediates pro- and anti-inflammatory responses during LPS-induced systemic inflammation in mice

J. Schneiders, Franziska Fuchs, Jelena Damm, +5

Brain Behavior and Immunity

InflammationCytokineImmune RegulationImmunologyChronic Inflammation +9

Spatiotemporal nuclear factor interleukin‐6 expression in the rat brain during lipopolysaccharide‐induced fever is linked to sustained hypothalamic inflammatory target gene induction

Jelena Damm, Giamal N. Luheshi, Rüdiger Gerstberger, +2

The Journal of Comparative Neurology

Immune RegulationImmunologyEntire BrainImportant Transcription FactorInnate Immunity +23

C-Reactive Protein Stimulates Nicotinic Acetylcholine Receptors to Control ATP-Mediated Monocytic Inflammasome Activation

Katrin Richter, Sabrina Sagawe, Andreas Hecker, +17

Frontiers in Immunology

The putative JAK-STAT inhibitor AG490 exacerbates LPS-fever, reduces sickness behavior, and alters the expression of pro- and anti-inflammatory genes in the rat brain

Jelena Damm, Lois M. Harden, Rüdiger Gerstberger, +2

Neuropharmacology

InflammationPsychoneuroimmunologyAutoimmune DiseaseAnti-inflammatory GenesMedicine +11

Activation of the inflammatory transcription factor nuclear factor interleukin-6 during inflammatory and psychological stress in the brain

Franziska Fuchs, Jelena Damm, Rüdiger Gerstberger, +2

Journal of Neuroinflammation

Critical role for peripherally-derived interleukin-10 in mediating the thermoregulatory manifestations of fever and hypothermia in severe forms of lipopolysaccharide-induced inflammation

Lois M. Harden, Christoph Rummel, Helen P. Laburn, +5

Pflügers Archiv - European Journal of Physiology

InflammationHyperthermiaAutoimmune DiseaseThermoregulatory ManifestationsImmunology +10

SLPI Inhibits ATP-Mediated Maturation of IL-1β in Human Monocytic Leukocytes: A Novel Function of an Old Player

Anna Zakrzewicz, Katrin Richter, Dariusz Zakrzewicz, +12

Frontiers in Immunology

Surfactant inhibits ATP-induced release of interleukin-1β via nicotinic acetylcholine receptors

Sören J. Backhaus, Anna Zakrzewicz, Katrin Richter, +10

Journal of Lipid Research

LPS Primes Brain Responsiveness to High Mobility Group Box-1 Protein

Verena Peek, Lois M. Harden, Jelena Damm, +9

Pharmaceuticals