Germline mutations in FH confer predisposition to malignant pheochromocytomas and paragangliomas

Luis Jaime Castro‐Vega, Alexandre Buffet, Aguirre A. de Cubas, +19

Human Molecular Genetics

Fh GeneTumor BiologySomatic VariantTumor HeterogeneityMedicine +11

Loss of succinate dehydrogenase activity results in dependency on pyruvate carboxylation for cellular anabolism

Charlotte Lussey‐Lepoutre, Kate E.R. Hollinshead, Christian Ludwig, +11

Nature Communications

Multi-omics analysis defines core genomic alterations in pheochromocytomas and paragangliomas

Luis Jaime Castro‐Vega, Éric Letouzé, Nelly Burnichon, +19

Nature Communications

Germline Mutations in the Mitochondrial 2-Oxoglutarate/Malate Carrier <i>SLC25A11</i> Gene Confer a Predisposition to Metastatic Paragangliomas

Alexandre Buffet, Aurélie Morin, Luis-Jaime Castro-Vega, +16

Cancer Research

Thrombospondin-1 Triggers Cell Migration and Development of Advanced Prostate Tumors

Virginie Firlej, Jacques R.R. Mathieu, Cristèle Gilbert, +8

Cancer Research

TET-Mediated Hypermethylation Primes SDH-Deficient Cells for HIF2α-Driven Mesenchymal Transition

Aurélie Morin, Judith Goncalves, Sophie Moog, +8

Cell Reports

Deciphering the molecular basis of invasiveness in <i>Sdhb</i>-deficient cells

Céline Loriot, Mélanie J. Domingues, Adeline Berger, +10

Oncotarget

Sdhb KnockoutSignal TransductionTumor MicroenvironmentSdhb LossMedicine +11

<i>In Vivo</i> Detection of Succinate by Magnetic Resonance Spectroscopy as a Hallmark of <i>SDH</i> x Mutations in Paraganglioma

Charlotte Lussey‐Lepoutre, Alexandre Bellucci, Aurélie Morin, +18

Clinical Cancer Research

Loss of SDHB Promotes Dysregulated Iron Homeostasis, Oxidative Stress, and Sensitivity to Ascorbate

Judith Goncalves, Sophie Moog, Aurélie Morin, +17

Cancer Research

SIRNA-Directed In Vivo Silencing of Androgen Receptor Inhibits the Growth of Castration-Resistant Prostate Carcinomas

Daniel Compagno, Carole Merle, Aurélie Morin, +6

PLoS ONE