The Transcriptional Coactivator Yes-Associated Protein Drives p73 Gene-Target Specificity in Response to DNA Damage

Sabrina Strano, Olimpia Monti, Natalia Pediconi, +10

Molecular Cell

Genome InstabilityTranscriptional RegulationDna DamageNatural SciencesGenetics +7

Recurrent inactivation of STAG2 in bladder cancer is not associated with aneuploidy

Cristina Balbás-Martínez, Ana Sagrera, Enrique Carrillo de Santa Pau, +29

Nature Genetics

Tumor BiologyUrologyGenitourinary CancerMedicinePathology +5

PML, YAP, and p73 Are Components of a Proapoptotic Autoregulatory Feedback Loop

Eleonora Lapi, Silvia Di Agostino, Sara Donzelli, +8

Molecular Cell

Signal TransductionMolecular PhysiologyPhysiologyNeurotransmitterNeuropeptide Receptor +6

Mutant p53 gain of function: reduction of tumor malignancy of human cancer cell lines through abrogation of mutant p53 expression

Gianluca Bossi, Eleonora Lapi, Sabrina Strano, +3

Oncogene

Mutant P53 ExpressionMedicineOncogenic AgentMutant P53 GainCancer Biology +8

Autophagic activity dictates the cellular response to oncogenic RAS

Yihua Wang, Xiao Dan Wang, Eleonora Lapi, +9

Proceedings of the National Academy of Sciences

The Lats2 tumor suppressor augments p53-mediated apoptosis by promoting the nuclear proapoptotic function of ASPP1

Yael Aylon, Yaara Ofir-Rosenfeld, Norikazu Yabuta, +4

Genes & Development

Urothelial organoids originating from Cd49fhigh mouse stem cells display Notch-dependent differentiation capacity

Catarina P. Santos, Eleonora Lapi, Jaime Martínez de Villarreal, +8

Nature Communications

Notch-dependent Differentiation CapacityStem Cell BiologyCell SpecializationTranscriptional RegulationTissue Development +19

Essential Roles of Cohesin STAG2 in Mouse Embryonic Development and Adult Tissue Homeostasis

Magali De Koninck, Eleonora Lapi, Claudio Badía-Careaga, +8

Cell Reports

S100A2 gene is a direct transcriptional target of p53 homologues during keratinocyte differentiation

Eleonora Lapi, Anthony J. Iovino, Giulia Fontemaggi, +7

Oncogene

Skin DevelopmentTranscriptional RegulationS100a2 GeneCell RegulationGenetics +6

SUMO-modified nuclear cyclin D1 bypasses Ras-induced senescence

X D Wang, Eleonora Lapi, Alice Sullivan, +4

Cell Death and Differentiation

Cell RegulationCellular SenescenceCell CycleMedicineCell Biology +2