Predominance of the autoimmune response to myelin oligodendrocyte glycoprotein (MOG) in multiple sclerosis: Reactivity to the extracellular domain of MOG is directed against three main regions

Nicole Kerlero de Rosbo, Michael A. Hoffman, Itzhack Mendel, +7

European Journal of Immunology

Laquinimod arrests experimental autoimmune encephalomyelitis by activating the aryl hydrocarbon receptor

Joel Kaye, Victor Piryatinsky, Tal Birnberg, +16

Proceedings of the National Academy of Sciences

Aryl Hydrocarbon Receptor Activation in Astrocytes by Laquinimod Ameliorates Autoimmune Inflammation in the CNS

Veit Rothhammer, Jessica E. Kenison, Emily Tjon, +6

Neurology Neuroimmunology & Neuroinflammation

Modes of cell:cell communication in the immune system

Ca Janeway, Kim Bottomly, Jay B. Horowitz, +3

The Journal of Immunology

Adaptive Immune SystemImmunologyImmunodominanceAntigen ProcessingT Cells +15

The influence of natural antibody specificity on antigen immunogenicity

Lorenzo Benatuil, Joel Kaye, Robert F. Rich, +3

European Journal of Immunology

Humoral ResponseImmunologyImmunodominancePathologyImmunotherapy +15

AL101, a gamma-secretase inhibitor, has potent antitumor activity against adenoid cystic carcinoma with activated NOTCH signaling

Renata Ferrarotto, Vasudha Mishra, Elad Herz, +17

Cell Death and Disease

Ex vivo transduction of human dermal tissue structures for autologous implantation production and delivery of therapeutic proteins

Einat Brill‐Almon, Baruch S. Stern, Daniel Afik, +8

Molecular Therapy

Tissue EngineeringEngineeringImmunologyBiofabricationTissue Transplantation +25

Clinical disease course and survival outcomes following disease recurrence in adenoid cystic carcinoma with and without NOTCH signaling pathway activation

Laura Feeney, Brindley Hapuarachi, Helen Adderley, +7

Oral Oncology

Induction of T cell tolerance to a protein expressed in the cytoplasm through retroviral‐mediated gene transfer

Chaorui Tian, Jessamyn Bagley, Joel Kaye, +1

The Journal of Gene Medicine

A novel cytidine analog, RX-3117, shows potent efficacy in xenograft models, even in tumors that are resistant to gemcitabine.

Mi Yang, Young Bok Lee, Chang‐Ho Ahn, +7

PubMed

Chemoprevention StrategyXenograft ModelsTgi 38PharmacotherapyTumor Biology +17