D‐Serine is a key determinant of glutamate toxicity in amyotrophic lateral sclerosis

Jumpei Sasabe, Tomohiro Chiba, Marina Yamada, +4

The EMBO Journal

Amyloid-β causes memory impairment by disturbing the JAK2/STAT3 axis in hippocampal neurons

Tomohiro Chiba, Marina Yamada, Jumpei Sasabe, +4

Molecular Psychiatry

Neurodegenerative DiseasesJak2/stat3 AxisDegenerative PathologyProtein MisfoldingNeurology +4

Inhaled Hydrogen Sulfide Prevents Neurodegeneration and Movement Disorder in a Mouse Model of Parkinson's Disease

Kotaro Kida, Marina Yamada, Kentaro Tokuda, +4

Antioxidants and Redox Signaling

Mptp AdministrationMedicineHydrogen SulfidePhysiologyNeuropharmacology +12

Inflammatory stimuli induce inhibitory S-nitrosylation of the deacetylase SIRT1 to increase acetylation and activation of p53 and p65

Shohei Shinozaki, Kyungho Chang, Michihiro Sakai, +14

Science Signaling

Thiosulfate Mediates Cytoprotective Effects of Hydrogen Sulfide Against Neuronal Ischemia

Eizo Marutani, Marina Yamada, Tomoaki Ida, +10

Journal of the American Heart Association

Involvement of c‐Jun N‐terminal kinase in amyloid precursor protein‐mediated neuronal cell death

Yuichi Hashimoto, Osahiko Tsuji, Takako Niikura, +12

Journal of Neurochemistry

A humanin derivative, S14G‐HN, prevents amyloid‐β‐induced memory impairment in mice

Hirohisa Tajima, Masaoki Kawasumi, Tomohiro Chiba, +9

Journal of Neuroscience Research

Development of a Femtomolar-Acting Humanin Derivative Named Colivelin by Attaching Activity-Dependent Neurotrophic Factor to Its N Terminus: Characterization of Colivelin-Mediated Neuroprotection against Alzheimer's Disease-Relevant Insults<i>In Vitro</i>and<i>In Vivo</i>

Tomohiro Chiba, Marina Yamada, Yuichi Hashimoto, +7

Journal of Neuroscience

Liver-specific Inducible Nitric-oxide Synthase Expression Is Sufficient to Cause Hepatic Insulin Resistance and Mild Hyperglycemia in Mice

Shohei Shinozaki, Cheol Soo Choi, Nobuyuki Shimizu, +6

Journal of Biological Chemistry

Metabolic DisorderImmunologyInsulin ReceptorFatty Liver DiseaseMild Hyperglycemia +20

The Cytoplasmic Domain of Alzheimer’s Amyloid-β Protein Precursor Causes Sustained Apoptosis Signal-Regulating Kinase 1/c-Jun NH2-Terminal Kinase-Mediated Neurotoxic Signal via Dimerization

Yuichi Hashimoto, Takako Niikura, Tomohiro Chiba, +11

Journal of Pharmacology and Experimental Therapeutics