Timothy H. Yosca

Iron(IV)hydroxide p <i>K</i> _a and the Role of Thiolate Ligation in C–H Bond Activation by Cytochrome P450

Timothy H. Yosca, Jonathan Rittle, Courtney M. Krest et al. · Science · 2013 · 326 citations

Iron Metabolism, Molecular Biology, Chemical Biology +17

Significantly shorter Fe–S bond in cytochrome P450-I is consistent with greater reactivity relative to chloroperoxidase

Courtney M. Krest, Alexey Silakov, Jonathan Rittle et al. · Nature Chemistry · 2015 · 109 citations · Full text

Shorter Fe–s Bond, Bioorganic Chemistry, Biochemistry +11

Direct Observation of Oxygen Rebound with an Iron-Hydroxide Complex

Jan Paulo T. Zaragoza, Timothy H. Yosca, Maxime A. Siegler et al. · Journal of the American Chemical Society · 2017 · 91 citations

Bioorganic Chemistry, Engineering, Rebound Mechanism +19

Characterization of a selenocysteine-ligated P450 compound I reveals direct link between electron donation and reactivity

Elizabeth L. Onderko, Alexey Silakov, Timothy H. Yosca et al. · Nature Chemistry · 2017 · 86 citations

Aldo-keto Reductase, Biochemistry, Selenocysteine-ligated P450 Compound +6

Oxygen-Atom Transfer Reactivity of Axially Ligated Mn(V)–Oxo Complexes: Evidence for Enhanced Electrophilic and Nucleophilic Pathways

Heather M. Neu, Tzuhsiung Yang, Regina A. Baglia et al. · Journal of the American Chemical Society · 2014 · 82 citations · Full text

Engineering, Theoretical Inorganic Chemistry, Molecular Biology +18