Molecular evidence of synaptic pathology in the CA1 region in schizophrenia

Natalie Matosin, Francesca Fernandez, Jeremy S. Lum, +6

Schizophrenia

NeuropsychologyNeurophysiological BiomarkersSocial SciencesPsd95 Protein ExpressionMolecular Evidence +18

Preclinical and Clinical Evidence of DNA Methylation Changes in Response to Trauma and Chronic Stress

Natalie Matosin, Cristiana Cruceanu, Elisabeth B. Binder

Chronic Stress

Epigenetic ChangeGeneticsDna MethylationGenetic EpidemiologyEpigenetics +18

Homer1/mGluR5 Activity Moderates Vulnerability to Chronic Social Stress

Klaus V. Wagner, Jakob Hartmann, Christiana Labermaier, +18

Neuropsychopharmacology

PsychopathologyChronic Social StressStress HormoneStressPsychology +5

Metabotropic glutamate receptor mGluR2/3 and mGluR5 binding in the anterior cingulate cortex in psychotic and nonpsychotic depression, bipolar disorder and schizophrenia: implications for novel mGluR-based therapeutics

Natalie Matosin, Francesca Fernandez, Elisabeth Frank, +4

Journal of Psychiatry and Neuroscience

Associations of psychiatric disease and ageing with FKBP5 expression converge on superficial layer neurons of the neocortex

Natalie Matosin, Janine Arloth, Darina Czamara, +33

Acta Neuropathologica

Psychiatric DisordersNeuropsychiatryNeurochemical BiomarkersFkbp5 Expression ConvergeFkbp5 Gex Levels +16

Alterations of mGluR5 and its endogenous regulators Norbin, Tamalin and Preso1 in schizophrenia: towards a model of mGluR5 dysregulation

Natalie Matosin, Francesca Fernandez, Samantha J. Fung, +6

Acta Neuropathologica

NeuropsychologyMolecular NeurosciencePsychiatryPsychotic DisorderMedicine +9

Effects of common GRM5 genetic variants on cognition, hippocampal volume and mGluR5 protein levels in schizophrenia

Natalie Matosin, Kelly A. Newell, Yann Quidé, +4

Brain Imaging and Behavior

Neuroimaging BiomarkersCognitive SciencePsychiatryPsychotic DisorderMedicine +10

Metabotropic glutamate receptor 5 binding and protein expression in schizophrenia and following antipsychotic drug treatment

Natalie Matosin, Elisabeth Frank, Chao Deng, +2

Schizophrenia Research

NeuropsychologyProtein ExpressionPsychiatryPsychotic DisorderMedicine +10

Metabotropic glutamate receptor 5, and its trafficking molecules Norbin and Tamalin, are increased in the CA1 hippocampal region of subjects with schizophrenia

Natalie Matosin, Francesca Fernandez, Jeremy S. Lum, +4

Schizophrenia Research

NeuropsychologyPsychiatryTrafficking Molecules NorbinCa1 Hippocampal RegionNeurotransmitter +8

Single-nucleus transcriptomic profiling of human orbitofrontal cortex reveals convergent effects of aging and psychiatric disease

Anna S. Fröhlich, Nathalie Gerstner, Miriam Gagliardi, +12

Nature Neuroscience