Allele-Specific HLA Loss and Immune Escape in Lung Cancer Evolution

Nicholas McGranahan, Rachel Rosenthal, Crispin T. Hiley, +218

Cell

Neoantigen-directed immune escape in lung cancer evolution

Rachel Rosenthal, Elizabeth Larose Cadieux, Roberto Salgado, +25

Nature

ImmunologyImmunoeditingBronchial NeoplasmLung CancerMedicine +2

Fc Effector Function Contributes to the Activity of Human Anti-CTLA-4 Antibodies

Frederick Arce Vargas, Andrew J.S. Furness, Kevin Litchfield, +20

Cancer Cell

Fc-Optimized Anti-CD25 Depletes Tumor-Infiltrating Regulatory T Cells and Synergizes with PD-1 Blockade to Eradicate Established Tumors

Frederick Arce Vargas, Andrew J.S. Furness, Isabelle Solomon, +245

Immunity

Pan-cancer deconvolution of tumour composition using DNA methylation

Ankur Chakravarthy, Andrew J.S. Furness, Kroopa Joshi, +10

Nature Communications

Determinants of anti-PD-1 response and resistance in clear cell renal cell carcinoma

Lewis Au, Emine Hatipoglu, Marc Robert de Massy, +62

Cancer Cell

Spatial heterogeneity of the T cell receptor repertoire reflects the mutational landscape in lung cancer

Kroopa Joshi, Marc Robert de Massy, Mazlina Ismail, +31

Nature Medicine

Systems BiologySomatic VariantMutational LandscapeTumor HeterogeneitySpatial Heterogeneity +9

Anti-programmed cell death-1 therapy and insulin-dependent diabetes: a case report

Juan Martín-Liberal, Andrew J.S. Furness, Kroopa Joshi, +3

Cancer Immunology Immunotherapy

Diabetes ManagementMedicineInsulin ManagementDiabetesCell Death +7

Quantitative Characterization of the T Cell Receptor Repertoire of Naïve and Memory Subsets Using an Integrated Experimental and Computational Pipeline Which Is Robust, Economical, and Versatile

Theres Oakes, James Heather, Katharine Best, +11

Frontiers in Immunology

The T cell differentiation landscape is shaped by tumour mutations in lung cancer

Ehsan Ghorani, James L. Reading, Jake Y. Henry, +298

Nature Cancer

Somatic VariantTumor HeterogeneityMedicineTumour MutationsPathology +7