Brian Murphy

Phase 2 Trial of Baxdrostat for Treatment-Resistant Hypertension

Mason W. Freeman, Yuan‐Di C. Halvorsen, William Marshall et al. · New England Journal of Medicine · 2022 · 313 citations · Full text

Results from a phase 1, randomized, double-blind, multiple ascending dose study characterizing the pharmacokinetics and demonstrating the safety and selectivity of the aldosterone synthase inhibitor baxdrostat in healthy volunteers

Mason W. Freeman, Mary Bond, Brian Murphy et al. · Hypertension Research · 2022 · 62 citations · Full text

Cardiovascular Pharmacology, Pharmacotherapy, Physiologically-based Pharmacokinetic Modeling +18

Results from a Phase 1 Study Assessing the Pharmacokinetics of the Aldosterone Synthase Inhibitor Baxdrostat in Participants with Varying Degrees of Renal Function

Mason W. Freeman, Yuan‐Di C. Halvorsen, Mary Lou Bond et al. · Clinical Pharmacology in Drug Development · 2024 · 14 citations · Full text

Results From a Randomized, Open-Label, Crossover Study Evaluating the Effect of the Aldosterone Synthase Inhibitor Baxdrostat on the Pharmacokinetics of Metformin in Healthy Human Subjects

Mason W. Freeman, Mary Bond, Brian Murphy et al. · American Journal of Cardiovascular Drugs · 2023 · 11 citations · Full text