Wenhui Yao

Icariin Prevents Extracellular Matrix Accumulation and Ameliorates Experimental Diabetic Kidney Disease by Inhibiting Oxidative Stress via GPER Mediated p62-Dependent Keap1 Degradation and Nrf2 Activation

Kai Wang, Xiulan Zheng, Zhenzhen Pan et al. · Frontiers in Cell and Developmental Biology · 2020 · 63 citations · Full text

Inflammation, Type 1, Renal Function +15

Hierarchical virtual screening of the dual MMP-2/HDAC-6 inhibitors from natural products based on pharmacophore models and molecular docking

Yijun Wang, Limei Yang, Jiaying Hou et al. · Journal of Biomolecular Structure and Dynamics · 2018 · 35 citations

Hierarchical Virtual Screening, Tumor Biology, Medicinal Chemistry +15

Icariin ameliorates endothelial dysfunction in type 1 diabetic rats by suppressing ER stress via the PPARα/Sirt1/AMPKα pathway

Wenhui Yao, Kai Wang, Xiniao Wang et al. · Journal of Cellular Physiology · 2020 · 22 citations

Screening for the selective inhibitors of MMP-9 from natural products based on pharmacophore modeling and molecular docking in combination with bioassay experiment, hybrid QM/MM calculation, and MD simulation

Jiaying Hou, Qing Zou, Yijun Wang et al. · Journal of Biomolecular Structure and Dynamics · 2018 · 18 citations

AR/RKIP pathway mediates the inhibitory effects of icariin on renal fibrosis and endothelial-to-mesenchymal transition in type 2 diabetic nephropathy

Wenhui Yao, Rongpin Tao, Yue Xu et al. · Journal of Ethnopharmacology · 2023 · 16 citations

Inflammation, Ar/rkip Pathway, Urology +13