Mithila A. Sawant

AECHL-1 targets breast cancer progression via inhibition of metastasis, prevention of EMT and suppression of Cancer Stem Cell characteristics

Aparajita Dasgupta, Mithila A. Sawant, Gayatri Kavishwar et al. · Scientific Reports · 2016 · 18 citations · Full text

Medicine, Oncology, Pharmacology +17

AECHL-1, a novel triterpenoid, targets tumor neo-vasculature and impairs the endothelial cell cytoskeleton

Aparajita Dasgupta, Mithila A. Sawant, Manish S Lavhale et al. · Angiogenesis · 2015 · 16 citations · Full text

Medicine, Oncology, Pharmacology +17

Novel triterpenoid AECHL-1 induces apoptosis in breast cancer cells by perturbing the mitochondria–endoplasmic reticulum interactions and targeting diverse apoptotic pathways

Mithila A. Sawant, Aparajita Dasgupta, Manish S Lavhale et al. · Biochimica et Biophysica Acta (BBA) - General Subjects · 2016 · 15 citations · Full text

Medicine, Oncology, Pharmacology +17

Prevention of Mitochondrial Membrane Permeabilization and Pancreatic β‐Cell Death by an Enantioenriched, Macrocyclic Small Molecule

Ravikumar Jimmidi, Govardhan K. Shroff, B. Ramesh Reddy et al. · European Journal of Organic Chemistry · 2014 · 10 citations

Life Sciences, Biochemistry, Medicinal Chemistry +17

A novel SOD mimic with a redox-modulating mn (II) complex, ML1 attenuates high glucose-induced abnormalities in intracellular Ca 2+ transients and prevents cardiac cell death through restoration of mitochondrial function

Vasundhara Kain, Mithila A. Sawant, Aparajita Dasgupta et al. · Biochemistry and Biophysics Reports · 2016 · 10 citations · Full text

Life Sciences, Cardiology, Cell Biology +17