Yannick Laplante

Estradiol and estrone C-16 derivatives as inhibitors of type 1 17β-hydroxysteroid dehydrogenase: Blocking of ER+ breast cancer cell proliferation induced by estrone

Yannick Laplante, Christine Cadot, Michelle-Audrey Fournier et al. · Bioorganic & Medicinal Chemistry · 2007 · 68 citations · Full text

Life Sciences, Biochemistry, Medicinal Chemistry +17

Relative involvement of three 17β-hydroxysteroid dehydrogenases (types 1, 7 and 12) in the formation of estradiol in various breast cancer cell lines using selective inhibitors

Yannick Laplante, Claudine Rancourt, Donald Poirier · Molecular and Cellular Endocrinology · 2008 · 66 citations

Life Sciences, Biochemistry, Oncology +17

C6-(N,N-butyl-methyl-heptanamide) derivatives of estrone and estradiol as inhibitors of type 1 17β-hydroxysteroid dehydrogenase: Chemical synthesis and biological evaluation

Christine Cadot, Yannick Laplante, Fatima Kamal et al. · Bioorganic & Medicinal Chemistry · 2006 · 33 citations

Life Sciences, Biochemistry, Pharmacology +17

Proliferative effect of androst-4-ene-3,17-dione and its metabolites in the androgen-sensitive LNCaP cell line

Yannick Laplante, Donald Poirier · Steroids · 2007 · 24 citations

Life Sciences, Endocrinology, Oncology +11

Design, Synthesis and In Vitro Evaluation of 4-Androstene-3,17-dione/Adenosine Hybrid Compounds as Bisubstrate Inhibitors of Type 3 17β-Hydroxysteroid Dehydrogenase

Marie Bérubé, Yannick Laplante, Donald Poirier · Medicinal Chemistry · 2006 · 12 citations

Life Sciences, Medicinal Chemistry, Pharmacology +17