Hing C. Wong

Sequestosome 1/p62 Is a Polyubiquitin Chain Binding Protein Involved in Ubiquitin Proteasome Degradation

M. Lamar Seibenhener, Jeganathan Ramesh Babu, Thangiah Geetha et al. · Molecular and Cellular Biology · 2004 · 697 citations · Full text

Proteasome, Molecular Biology, Cell Death +18

Enhancing T cell therapy through TCR-signaling-responsive nanoparticle drug delivery

Li Tang, Yiran Zheng, Mariane B. Melo et al. · Nature Biotechnology · 2018 · 623 citations · Full text

T Cell Therapy, Nanomedicine, Cell-based Drug Delivery +4

ALT-803, an IL-15 superagonist, in combination with nivolumab in patients with metastatic non-small cell lung cancer: a non-randomised, open-label, phase 1b trial

John Wrangle, Vamsidhar Velcheti, Manish R. Patel et al. · The Lancet Oncology · 2018 · 410 citations

Il-15 Superagonist, Medicine, Immunology +8

First-in-human phase 1 clinical study of the IL-15 superagonist complex ALT-803 to treat relapse after transplantation

Rizwan Romee, Sarah Cooley, Melissa M. Berrien-Elliott et al. · Blood · 2018 · 397 citations · Full text

T cell sensing of antigen dose governs interactive behavior with dendritic cells and sets a threshold for T cell activation

Sarah E. Henrickson, Thorsten R. Mempel, Irina B. Mazo et al. · Nature Immunology · 2008 · 384 citations · Full text

T Cell Activation, Autoimmune Disease, Allergy +12