Thibaut Legigan

A mechanically interlocked molecular system programmed for the delivery of an anticancer drug

Romain Barat, Thibaut Legigan, Isabelle Tranoy‐Opalinski et al. · Chemical Science · 2015 · 163 citations · Full text

Pharmacy, Medicinal Chemistry, Oncology +13

Targeting the tumour microenvironment with an enzyme-responsive drug delivery system for the efficient therapy of breast and pancreatic cancers

Brigitte Renoux, Florian Raes, Thibaut Legigan et al. · Chemical Science · 2017 · 122 citations · Full text

Pharmacy, Oncology, Pharmaceutics +17

β-Glucuronidase-responsive prodrugs for selective cancer chemotherapy: An update

Isabelle Tranoy‐Opalinski, Thibaut Legigan, Romain Barat et al. · European Journal of Medicinal Chemistry · 2014 · 113 citations

Pharmacy, Medicinal Chemistry, Pharmacology +14

The First Generation of β‐Galactosidase‐Responsive Prodrugs Designed for the Selective Treatment of Solid Tumors in Prodrug Monotherapy

Thibaut Legigan, Jonathan Clarhaut, Isabelle Tranoy‐Opalinski et al. · Angewandte Chemie International Edition · 2012 · 109 citations

Pharmacy, Medicinal Chemistry, Pharmacology +15

Synthesis and Antitumor Efficacy of a β-Glucuronidase-Responsive Albumin-Binding Prodrug of Doxorubicin

Thibaut Legigan, Jonathan Clarhaut, Brigitte Renoux et al. · Journal of Medicinal Chemistry · 2012 · 80 citations

Pharmacy, Medicinal Chemistry, Pharmacology +15