Flávia Nathiely Silveira Fachel

Box-Behnken design optimization of mucoadhesive chitosan-coated nanoemulsions for rosmarinic acid nasal delivery—In vitro studies

Flávia Nathiely Silveira Fachel, Bruna Medeiros-Neves, Morgana Prá et al. · Carbohydrate Polymers · 2018 · 102 citations

Pharmacy, Pharmaceutics, Pharmacology +17

Chitosan-coated rosmarinic acid nanoemulsion nasal administration protects against LPS-induced memory deficit, neuroinflammation, and oxidative stress in Wistar rats

Flávia Nathiely Silveira Fachel, Luana Roberta Michels, Juliana H. Azambuja et al. · Neurochemistry International · 2020 · 42 citations

Pharmacy, Neuroscience, Pharmacology +16

Compatibility study of rosmarinic acid with excipients used in pharmaceutical solid dosage forms using thermal and non-thermal techniques

Kleyton Santos Veras, Flávia Nathiely Silveira Fachel, Vanessa Pittol et al. · Saudi Pharmaceutical Journal · 2019 · 40 citations · Full text

Pharmacy, Pharmaceutics, Pharmacology +17

Nasal administration of a temozolomide-loaded thermoresponsive nanoemulsion reduces tumor growth in a preclinical glioblastoma model

Luana Roberta Michels, Flávia Nathiely Silveira Fachel, Roselena Silvestri Schuh et al. · Journal of Controlled Release · 2023 · 40 citations

Pharmacy, Pharmaceutics, Pharmacology +14

Glioprotective Effect of Chitosan-Coated Rosmarinic Acid Nanoemulsions Against Lipopolysaccharide-Induced Inflammation and Oxidative Stress in Rat Astrocyte Primary Cultures

Flávia Nathiely Silveira Fachel, Morgana Prá, Juliana H. Azambuja et al. · Cellular and Molecular Neurobiology · 2019 · 36 citations · Full text

Medicine, Neurobiology, Pharmacology +16