Josephine Charlton

In vivo imaging of inflammation using an aptamer inhibitor of human neutrophil elastase

Josephine Charlton, Joseph A. Sennello, Drew Smith · Chemistry & Biology · 1997 · 160 citations · Full text

Inflammation, Vivo Imaging, Anti-inflammatory +10

In vitro selection of RNA-based irreversible inhibitors of human neutrophil elastase

Drew Smith, Gary P. Kirschenheuter, Josephine Charlton et al. · Chemistry & Biology · 1995 · 74 citations · Full text

Rna-based Irreversible Inhibitors, Human Neutrophil Elastase, Engineering +9

Protective effects of an aptamer inhibitor of neutrophil elastase in lung inflammatory injury

Nicolas M. Bless, Drew Smith, Josephine Charlton et al. · Current Biology · 1997 · 68 citations · Full text

Inflammation, Acute Lung Injury, Anti-inflammatory +13

Highly Potent Irreversible Inhibitors of Neutrophil Elastase Generated by Selection from a Randomized DNA−Valine Phosphonate Library

Josephine Charlton, Gary P. Kirschenheuter, Drew Smith · Biochemistry · 1997 · 57 citations

Inhibitory Activity, Medicinal Chemistry, Bioorganic Chemistry +15

Estimation of SELEX pool size by measurement of DNA renaturation rates

Josephine Charlton, Drew Smith · RNA · 1999 · 26 citations

Genetics, Dna Analysis, Molecular Biology +23