Linking the p53 tumour suppressor pathway to somatic cell reprogramming

Teruhisa Kawamura, Jotaro Suzuki, Yunyuan V. Wang, +5

Nature

Tumor BiologySomatic VariantSomatic Cell GeneticsMedicineTumor Suppressor +6

Rem2 GTPase maintains survival of human embryonic stem cells as well as enhancing reprogramming by regulating p53 and cyclin D₁

Michael J. Edel, Cristina Menchón, Sergio Ménendez, +3

Genes & Development

Ubiquitin-independent degradation of p53 mediated by high-risk human papillomavirus protein E6

Suzanne Camus, Sergio Ménendez, Chit Fang Cheok, +2

Oncogene

PathologyProtein DegradationMedicineCell BiologyCancer Research +4

Increased dosage of tumor suppressors limits the tumorigenicity of iPS cells without affecting their pluripotency

Sergio Ménendez, Suzanne Camus, Aida Herreria, +11

Aging Cell

ImmunologyEmbryonic StemFull PluripotencyTumor BiologyStem Cells +14

Identification of phosphorylase kinase as a novel therapeutic target through high-throughput screening for anti-angiogenesis compounds in zebrafish

Suzanne Camus, Celia Quevedo, Sergio Ménendez, +8

Oncogene

Signal TransductionAngiogenesisMedicineReceptor Tyrosine KinaseVascular Biology +8

The degradation of p53 and its major E3 ligase Mdm2 is differentially dependent on the proteasomal ubiquitin receptor S5a

Alison Sparks, Saurabh Dayal, Joyutpal Das, +3

Oncogene

Reprogramming Roadblocks Are System Dependent

Eleni Chantzoura, Stavroula Skylaki, Sergio Ménendez, +6

Stem Cell Reports

Oligomerization of the Human ARF Tumor Suppressor and Its Response to Oxidative Stress

Sergio Ménendez, Zeb Khan, David Coomber, +3

Journal of Biological Chemistry

The p53 isoforms are differentially modified by Mdm2

Suzanne Camus, Sergio Ménendez, Kenneth Fernandes, +5

Cell Cycle

Molecular BiologyCancer BiologyTumor BiologyTranscriptional RegulationP53 Isoforms +15

Regulation of the p14ARF promoter by DNA methylation

Vinay Badal, Sergio Ménendez, David Coomber, +1

Cell Cycle

P14arf PromoterEpigenetic ChangeGeneticsDna MethylationMolecular Biology +15