Concepedia
Statistics
Publications
9
Citations
194
H-Index
Active since
2018
Affiliations
Duke University(Current)
Bolder Biotechnology, Inc.
University of North Carolina at Chapel Hill
University of Michigan
Scott A. Scarneo is an author at Duke University specializing in inflammation, pathology, and oxidative stress.
Top concepts
FibrosisMedicinePathologyImmunologyDermatologySclerodermaCell BiologyInflammationPharmacologyCell Signaling
Publications per year
2018–2023
Pharmacological inhibition of TAK1, with the selective inhibitor takinib, alleviates clinical manifestation of arthritis in CIA mice
Scott A. Scarneo, Liesl S. Eibschutz, Phillip J. Bendele et al. · Arthritis Research & Therapy · 2019 · 49 citations · Full text
Genetic and pharmacological validation of TAK1 inhibition in macrophages as a therapeutic strategy to effectively inhibit TNF secretion
Scott A. Scarneo, Antoine Mansourati, Liesl S. Eibschutz et al. · Scientific Reports · 2018 · 32 citations · Full text
A highly selective inhibitor of interleukin-1 receptor–associated kinases 1/4 (IRAK-1/4) delineates the distinct signaling roles of IRAK-1/4 and the TAK1 kinase
Scott A. Scarneo, Philip F. Hughes, Kelly W. Yang et al. · Journal of Biological Chemistry · 2019 · 26 citations · Full text
Development and Efficacy of an Orally Bioavailable Selective TAK1 Inhibitor for the Treatment of Inflammatory Arthritis
Scott A. Scarneo, Philip F. Hughes, Robert Freeze et al. · ACS Chemical Biology · 2022 · 23 citations · Full text
Pharmacological inhibition of TAK1 prevents and induces regression of experimental organ fibrosis
Swarna Bale, Priyanka Verma, Bharath Yalavarthi et al. · JCI Insight · 2023 · 20 citations · Full text
Tak1 Prevents, Immunology, Immune Regulation +22
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