Mitochondrial dysfunction during hypoxia/reoxygenation and its correction by anaerobic metabolism of citric acid cycle intermediates

Joel M. Weinberg, Manjeri A. Venkatachalam, Nancy F. Roeser, +1

Proceedings of the National Academy of Sciences

Anaerobic and aerobic pathways for salvage of proximal tubules from hypoxia-induced mitochondrial injury

Joel M. Weinberg, Manjeri A. Venkatachalam, Nancy F. Roeser, +4

American Journal of Physiology-Renal Physiology

Quantitative assessment of neuroprotection against NMDA-induced brain injury

John W. McDonald, Nancy F. Roeser, Faye S. Silverstein, +1

Experimental Neurology

Traumatic Brain InjuryMedicineBrain InjuryNeurologyNeuroscience +6

Role of increased cytosolic free calcium in the pathogenesis of rabbit proximal tubule cell injury and protection by glycine or acidosis.

Joel M. Weinberg, Julie A. Davis, Nancy F. Roeser, +1

Journal of Clinical Investigation

Cytosolic Free CalciumCytoskeletonCellular PhysiologyOxidative StressMedium Ca2+ +18

Structural requirements for protection by small amino acids against hypoxic injury in kidney proximal tubules ¹

Joel M. Weinberg, Manjeri A. Venkatachalam, Ricardo Garzo-Quintero, +2

The FASEB Journal

Accumulation of nonesterified fatty acids causes the sustained energetic deficit in kidney proximal tubules after hypoxia-reoxygenation

Thorsten Feldkamp, Andreas Kribben, Nancy F. Roeser, +2

American Journal of Physiology-Renal Physiology

Lipid PeroxidationMitochondrial BiologySevere HypoxiaRedox BiologyOxidative Stress +18

Protection of human umbilical vein endothelial cells by glycine and structurally similar amino acids against calcium and hydrogen peroxide-induced lethal cell injury.

Joel M. Weinberg, James Varani, Kent J. Johnson, +4

PubMed

Differential cytoprotection by glycine against oxidant damage to proximal tubule cells

Keizo Sogabe, Nancy F. Roeser, Manjeri A. Venkatachalam, +1

Kidney International

Oxidant DamageBiochemistryMedicineTubule CellsNatural Sciences +7

Cyclophilin D and the mitochondrial permeability transition in kidney proximal tubules after hypoxic and ischemic injury

Jeong Soon Park, Ratna Pasupulati, Thorsten Feldkamp, +2

American Journal of Physiology-Renal Physiology

Lipid PeroxidationMitochondrial Permeability TransitionCell DeathCyclophilin DCytoskeleton +20

Glycine-protected, hypoxic, proximal tubules develop severely compromised energetic function

Joel M. Weinberg, Nancy F. Roeser, Julie A. Davis, +1

Kidney International

Energy MetabolismBiochemistryPhysiologyCatabolismMetabolism +5