Isabel Lorenzo-Castrillejo

Lawsone, Juglone, and β-Lapachone Derivatives with Enhanced Mitochondrial-Based Toxicity

Laura Anaissi‐Afonso, Sandra Oramas‐Royo, Jessel Ayra‐Plasencia et al. · ACS Chemical Biology · 2018 · 45 citations · Full text

Juglone Derivatives, Pharmaceutical Chemistry, Biochemistry +9

Synthesis and biological evaluation of naphthoquinone-coumarin conjugates as topoisomerase II inhibitors

Idaira Hueso-Falcón, Ángel Amesty, Laura Anaissi‐Afonso et al. · Bioorganic & Medicinal Chemistry Letters · 2016 · 39 citations · Full text

Pharmaceutical Chemistry, Biochemistry, Medicine +8

Pyranonaphthoquinone derivatives of eleutherin, ventiloquinone L, thysanone and nanaomycin A possessing a diverse topoisomerase II inhibition and cytotoxicity spectrum

Jonathan Sperry, Isabel Lorenzo-Castrillejo, Margaret A. Brimble et al. · Bioorganic & Medicinal Chemistry · 2009 · 37 citations

Medicinal Chemistry, Cytotoxicity Spectrum, Bioorganic Chemistry +13

Synthesis and study of antiproliferative, antitopoisomerase II, DNA-intercalating and DNA-damaging activities of arylnaphthalimides

Patricia Quintana-Espinoza, Jonay García-Luis, Ángel Amesty et al. · Bioorganic & Medicinal Chemistry · 2013 · 25 citations

Natural Sciences, Molecular Biology, Organic Chemistry +5

Yeast cytotoxic sensitivity to the antitumour agent β-lapachone depends mainly on oxidative stress and is largely independent of microtubule- or topoisomerase-mediated DNA damage

Cristina Ramos-Pérez, Isabel Lorenzo-Castrillejo, Oliver Quevedo et al. · Biochemical Pharmacology · 2014 · 18 citations

Yeast Cytotoxic Sensitivity, Biochemistry, Medicine +7