T. Hedley Carr

EGFR mutation detection in ctDNA from NSCLC patient plasma: A cross-platform comparison of leading technologies to support the clinical development of AZD9291

Kenneth S. Thress, Roz Brant, T. Hedley Carr et al. · Lung Cancer · 2015 · 493 citations · Full text

Medicine, Oncology, Pharmacology +17

Early ctDNA dynamics as a surrogate for progression-free survival in advanced breast cancer in the BEECH trial

Sarah Hrebien, Valentina Citi, Isaac García-Murillas et al. · Annals of Oncology · 2019 · 153 citations · Full text

Medicine, Oncology, Pharmacology +17

A Phase I Open-Label Study to Identify a Dosing Regimen of the Pan-AKT Inhibitor AZD5363 for Evaluation in Solid Tumors and in <i>PIK3CA</i> -Mutated Breast and Gynecologic Cancers

Udai Banerji, Emma Dean, José Alejandro Pérez Fidalgo et al. · Clinical Cancer Research · 2017 · 146 citations · Full text

Medicine, Oncology, Pharmacology +17

Optimisation of robust singleplex and multiplex droplet digital PCR assays for high confidence mutation detection in circulating tumour DNA

Vicky Rowlands, Andrzej Rutkowski, Elena Meuser et al. · Scientific Reports · 2019 · 112 citations · Full text

Medicine, Molecular Biology, Oncology +17

The National Lung Matrix Trial: translating the biology of stratification in advanced non-small-cell lung cancer

Gary Middleton, L. Crack, Sanjay Popat et al. · Annals of Oncology · 2015 · 81 citations · Full text

Medicine, Molecular Medicine, Oncology +17