Xiangwen Chen‐Deutsch

c-Jun N-terminal kinase 2 (JNK2) antagonizes the signaling of differentiation by JNK1 in human myeloid leukemia cells resistant to vitamin D

Xiangwen Chen‐Deutsch, Edward Garay, Jing Zhang et al. · Leukemia Research · 2009 · 28 citations · Full text

Hematological Malignancy, Signal Transduction, Cell Regulation +6

At-Risk Genomic Findings for Pediatric-Onset Disorders From Genome Sequencing vs Medically Actionable Gene Panel in Proactive Screening of Newborns and Children

Jorune Balciuniene, Ruby Liu, Lora Jh Bean et al. · JAMA Network Open · 2023 · 21 citations · Full text

Evidence from 2100 index cases supports genome sequencing as a first-tier genetic test

Fen Guo, Ruby Liu, Yinghong Pan et al. · Genetics in Medicine · 2023 · 19 citations · Full text

Bioinformatics, Genetic Testing, Medicine +11

Dual role of hematopoietic progenitor kinase 1 (HPK1) as a positive regulator of 1α,25-dihydroxyvitamin D-induced differentiation and cell cycle arrest of AML cells and as a mediator of vitamin D resistance

Xiangwen Chen‐Deutsch, George P. Studzinski · Cell Cycle · 2012 · 14 citations · Full text

The pan-caspase inhibitor Q-VD-OPh has anti-leukemia effects and can interact with vitamin D analogs to increase HPK1 signaling in AML cells

Xiangwen Chen‐Deutsch, Andrzej Kutner, Jonathan S. Harrison et al. · Leukemia Research · 2012 · 12 citations · Full text

Hematological Malignancy, Pan-caspase Inhibitor Q-vd-oph, Immunology +8