Concepedia

Chitra Mani

CM

Statistics

Publications

11

Citations

663

H-Index

11

Active since

1991

Affiliations

Lawrence Livermore National Laboratory(Current)

Pharmacyclics (United States)

Chitra Mani is an author at Lawrence Livermore National Laboratory specializing in medicine, pharmacology, and biochemistry.

Top concepts

Publications per year

1991–2015

11

Publications

11

Cytochrome P-450-mediated activation and irreversible binding of the antiestrogen tamoxifen to proteins in rat and human liver: possible involvement of flavin-containing monooxygenases in tamoxifen activation.

Chitra Mani, David Kupfer · PubMed · 1991 · 122 citations

, , +16

Metabolism of the antimammary cancer antiestrogenic agent tamoxifen. I. Cytochrome P-450-catalyzed N-demethylation and 4-hydroxylation.

Chitra Mani, Harry V. Gelboin, S. S. Park et al. · Drug Metabolism and Disposition · 1993 · 118 citations

A Phase I/II Multicenter, Open-Label Study of the Oral Histone Deacetylase Inhibitor Abexinostat in Relapsed/Refractory Lymphoma

Andrew M. Evens, Sriram Balasubramanian, Julie M. Vose et al. · Clinical Cancer Research · 2015 · 93 citations

Metabolism of the antimammary cancer antiestrogenic agent tamoxifen. II. Flavin-containing monooxygenase-mediated N-oxidation.

Chitra Mani, Ernest Hodgson, David Kupfer · Drug Metabolism and Disposition · 1993 · 81 citations

Involvement of cytochrome P4503A in catalysis of tamoxifen activation and covalent binding to rat and human liver microsomes

Chitra Mani, Robin E. Pearce, Andrew Parkinson et al. · Carcinogenesis · 1994 · 67 citations

1–5 of 11