Development of Oleanane-Type Triterpenes as a New Class of HCV Entry Inhibitors

Fei Yu, Qi Wang, Zhen Zhang, +15

Journal of Medicinal Chemistry

PharmacotherapyAntiviral DrugPharmaceutical ChemistryDrug ResistanceMolecular Pharmacology +16

Potential involvement of miR-375 in the premalignant progression of oral squamous cell carcinoma mediated via transcription factor KLF5

Wen Shi, Jing Yang, Siyuan Li, +8

Oncotarget

Potential InvolvementImmunologyPathologyCell DeathMrna Profiling +17

Daucosterol inhibits cancer cell proliferation by inducing autophagy through reactive oxygen species-dependent manner

Chuanke Zhao, Tiantian She, Lixin Wang, +6

Life Sciences

Cell AutophagyMitophagyCancer Cell ProliferationOxysterolChemoprevention Strategy +8

Inhibition of STAT5a by Naa10p contributes to decreased breast cancer metastasis

Yan Zeng, Li Min, Yong Han, +11

Carcinogenesis

Breast Cancer MetastasisBreast OncologyCancer MetastasisCancer BiologyMammary Gland Development +15

A VEGFR1 antagonistic peptide inhibits tumor growth and metastasis through VEGFR1-PI3K-AKT signaling pathway inhibition.

Zheng Zhou, Chuanke Zhao, Lixin Wang, +9

PubMed

ImmunologyCancer BiologyTumor BiologyAngiogenesisReceptor Tyrosine Kinase +18

Elucidation of the pharmacophore of echinocystic acid, a new lead for blocking HCV entry

Han Wang, Qi Wang, Sulong Xiao, +7

European Journal of Medicinal Chemistry

BiochemistryPharmacologyNew LeadEchinocystic AcidHcv Entry

Targeting Claudin 18.2 Using a Highly Specific Antibody Enables Cancer Diagnosis and Guided Surgery

Chuanke Zhao, Zhuona Rong, Jin Ding, +9

Molecular Pharmaceutics

Development of a novel albumin-based and maleimidopropionic acid-conjugated peptide with prolonged half-life and increased <i>in vivo</i> anti-tumor efficacy

Junnan Feng, Chuanke Zhao, Lixin Wang, +6

Theranostics

Sarsaparilla (Smilax Glabra Rhizome) Extract Inhibits Migration and Invasion of Cancer Cells by Suppressing TGF-β1 Pathway

Tiantian She, Chuanke Zhao, Junnan Feng, +5

PLoS ONE

Cell AdhesionSmilax Glabra RhizomeImmunologyCancer BiologyTumor Biology +14

Fibrinogen‐derived fibrinostatin inhibits tumor growth through anti‐angiogenesis

Chuanke Zhao, Yahui Su, Jianzhi Zhang, +7

Cancer Science