Concepedia

Magdalena M. Scharf

MM

6

Publications

100

Citations

6

H-Index

2019

Active since

Affiliations

Karolinska Institutet(Current)

Philipps University of Marburg

University of Copenhagen

Magdalena M. Scharf is an author at Karolinska Institutet specializing in medicinal chemistry, structural biology, and drug discovery.

ORCID

Top concepts

Publications per year

2019–2024

6

Publications

6

Pathway selectivity in Frizzleds is achieved by conserved micro-switches defining pathway-determining, active conformations

Lukas Grätz, Maria Kowalski-Jahn, Magdalena M. Scharf et al. · Nature Communications · 2023 · 23 citations · Full text

Comparative Docking to Distinct G Protein–Coupled Receptor Conformations Exclusively Yields Ligands with Agonist Efficacy

Magdalena M. Scharf, Moritz Bünemann, Jillian G. Baker et al. · Molecular Pharmacology · 2019 · 19 citations · Full text

A Focus on Unusual ECL2 Interactions Yields β<sub>2</sub>‐Adrenergic Receptor Antagonists with Unprecedented Scaffolds

Magdalena M. Scharf, Mirjam Zimmermann, Florian Wilhelm et al. · ChemMedChem · 2020 · 16 citations · Full text

Analyzing Kinase Similarity in Small Molecule and Protein Structural Space to Explore the Limits of Multi-Target Screening

Denis Schmidt, Magdalena M. Scharf, Dominique Sydow et al. · Molecules · 2021 · 16 citations · Full text

, , +23

Frizzleds act as dynamic pharmacological entities

Gunnar Schulte, Magdalena M. Scharf, Julien Bous et al. · Trends in Pharmacological Sciences · 2024 · 13 citations · Full text

Rows per page

1–5 of 6