Jean‐Noël Octave

Aggregated Tau activates NLRP3–ASC inflammasome exacerbating exogenously seeded and non-exogenously seeded Tau pathology in vivo

Ilie‐Cosmin Stancu, Niels Cremers, Hannah Vanrusselt et al. · Acta Neuropathologica · 2019 · 431 citations · Full text

A Novel mRNA of the A4 Amyloid Precursor Gene Coding for a Possibly Secreted Protein

Frédéric J. de Sauvage, Jean‐Noël Octave · Science · 1989 · 207 citations

Protein Secretion, Alzheimer's Disease, Biochemistry +13

Inhibitors of Amyloid Toxicity Based on β-sheet Packing of Aβ40 and Aβ42

Takeshi Sato, Pascal Kienlen‐Campard, Mahiuddin Ahmed et al. · Biochemistry · 2006 · 192 citations · Full text

Transgenic Expression of the Shortest Human Tau Affects Its Compartmentalization and Its Phosphorylation as in the Pretangle Stage of Alzheimer's Disease

Jean‐Pierre Brion, Günter Tremp, Jean‐Noël Octave · American Journal Of Pathology · 1999 · 191 citations

Alzheimer's Disease, Signal Transduction, Pretangle Stage +10

Intracellular Amyloid-β1–42, but Not Extracellular Soluble Amyloid-β Peptides, Induces Neuronal Apoptosis

Pascal Kienlen‐Campard, Sarah Miolet, Bernadette Tasiaux et al. · Journal of Biological Chemistry · 2002 · 188 citations · Full text

Induces Neuronal Apoptosis, Cell Death, Amyloid Precursor Protein +17