Justin Munro

Chemogenomics identifies acetyl-coenzyme A synthetase as a target for malaria treatment and prevention

Robert L. Summers, Charisse Flerida A. Pasaje, João Pedro Pisco et al. · Cell chemical biology · 2021 · 81 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +16

Preclinical characterization and target validation of the antimalarial pantothenamide MMV693183

Laura E. de Vries, Patrick A.M. Jansen, Catalina Barceló et al. · Nature Communications · 2022 · 41 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +17

Genetic ablation of the mitoribosome in the malaria parasite Plasmodium falciparum sensitizes it to antimalarials that target mitochondrial functions

Liqin Ling, Mulaka Maruthi, Justin Munro et al. · Journal of Biological Chemistry · 2020 · 39 citations · Full text

Life Sciences, Genetics, Molecular Biology +17

The mitochondrion of <i>Plasmodium falciparum</i> is required for cellular acetyl-CoA metabolism and protein acetylation

Sethu C. Nair, Justin Munro, Alexis Mann et al. · Proceedings of the National Academy of Sciences · 2023 · 18 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +16

Anti-inflammation and antimalarial profile of 5-pyridin-2-yl-1H-[1,2,4]triazole-3-carboxylic acid ethyl ester as a low molecular intermediate for hybrid drug synthesis

François Eya’ane Meva, Timothy J. Prior, David J. Evans et al. · Research on Chemical Intermediates · 2021 · 13 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +11